Vitamin D reduces risk of colon cancer

According to a study, published in theJournal of the National Cancer Institute, higher vitamin D levels are associated with a lower risk of colorectal cancer, particularly in women.NBC News
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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Conclusions: This study constructs a panel of potential prognostic model of left- and right-sided colon cancers, respectively. We also provide molecular biological alterations between left- and right-sided colon cancers.Cell Physiol Biochem 2018;48:475 –490
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
(MedPage Today) -- Positive FOBT tied to increased mortality from non-cancer causes
Source: MedPage Today Public Health - Category: American Health Source Type: news
CONCLUSION: Despite a more frequent presentation with advanced disease, colorectal cancer has a similar prognosis in pregnancy when compared with the general population. Diagnostic interventions and treatment should not be delayed due to the pregnancy but a balance between maternal and foetal wellbeing must always be kept in mind. PMID: 30010511 [PubMed - as supplied by publisher]
Source: Acta Chirurgica Belgica - Category: Surgery Tags: Acta Chir Belg Source Type: research
AbstractColorectal cancer (CRC) is a malignancy whose incidence is increasing globally, and there is a gender difference in the increasing risk. Evidence from hormone replacement therapy studies points to a role for circulating estrogens in suppressing the development of CRC. Estrogen receptor- β has been identified as a tumor suppressor, but other actions of estrogen may also contribute to the difference in CRC incidence between men and women. The KCNQ1/KCNE3 potassium channel is regulated by estrogen in order to modulate chloride secretion during the menstrual cycle; the effect of estro gen on the colon is to promot...
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research
DiscussionThe RETNET trial is a prospective, multicenter randomized controlled trial designed to determine the optimal embolotherapy technique for NET liver metastases.Trial registrationClinicalTrials.gov,NCT02724540. Registered on March 31, 2016.
Source: Trials - Category: Research Source Type: clinical trials
Zyxin is a member of the focal adhesion complex and plays a critical role in actin filament polymerization and cell motility. Several recent studies showed that Zyxin is a positive regulator of Yki/YAP (Yes-associated protein) signaling. However, little is known about the mechanisms by which Zyxin itself is regulated and...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: PNAS Plus Source Type: research
MONDAY, July 16, 2018 -- Even if it's not visible to the naked eye, blood in the stool can be serious -- a sign of a potentially fatal disease other than colon cancer, new research suggests. This could include circulatory, respiratory, digestive,...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Conclusion: Molecular mechanism and clinical efficacy of some of the emerging molecular targets for cancer chemotherapy have been briefly reviewed in the present article.
Source: Current Chemical Biology - Category: Biochemistry Source Type: research
Weight loss surgery may decrease a person's risk of developing hormone-related cancers, increase the chance of colon cancer, according to study in England.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
AbstractPurpose of reviewRecent studies demonstrate that normal human tissues accumulate substantial numbers of somatic mutations with aging, to levels comparable to their corresponding cancers. If mutations cause cancer, how do tissues avoid cancer when mutations are unavoidable?Recent findingsThe small intestines (SI) and colon accumulate similar numbers of replication errors, but SI adenocarcinoma is much rarer than colorectal cancer. Both the small and large intestines are subdivided into millions of small neighborhoods (crypts) that are maintained by small numbers of stem cells. To explain the SI cancer paradox, four ...
Source: Current Pathobiology Reports - Category: Laboratory Medicine Source Type: research
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