The Risk of Cardiovascular Disease, End-Stage Renal Disease, and Stroke in Post-Partum Women and their Fetuses after a Hypertensive Pregnancy.

The Risk of Cardiovascular Disease, End-Stage Renal Disease, and Stroke in Post-Partum Women and their Fetuses after a Hypertensive Pregnancy. Am J Physiol Regul Integr Comp Physiol. 2018 Jun 13;: Authors: Cunningham MW, LaMarca BD Abstract Women with hypertensive pregnancy complications are at greater risk of developing cardiovascular disease (CVD), metabolic diseases, stroke, and end-stage renal disease later in life. Pregnancy complications not only effect the mother's long-term health, but also the health of the fetus immediately after delivery and into adulthood. The health of the fetus until adulthood can be influenced by developmental programming, in which the fetus is exposed to insults that will ultimately affect the growth of the offspring and increase the offspring's risk of developing hypertension, coronary heart disease, metabolic disease, and chronic kidney disease in adulthood. Preeclampsia, the onset of hypertension during pregnancy, is one of the major risk factors for the development of renal, cerebral, and cardiovascular disease in the mother. Women with preeclampsia are at a 5-12 fold increased risk of developing end-stage renal disease (ESRD), 2 fold risk of stroke, and 2 fold risk of developing CVD later in life. In this review article, we will discuss 1. Preeclampsia, 2.the risk of developing CVD, renal disease, and stroke later in life for women with hypertensive pregnancies, 3.the effects of a hypertensive pr...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - Category: Physiology Authors: Tags: Am J Physiol Regul Integr Comp Physiol Source Type: research