The outcomes of radiotherapy in patients with ovarian carcinoma.

The outcomes of radiotherapy in patients with ovarian carcinoma. Eur J Gynaecol Oncol. 2016 08;37(4):461-468 Authors: Biedka M Abstract Relapses of ovarian cancer have poor prognosis, overall survival (OS) after recurrence depends on patient's performance status, his- tological cell type, size and number of the relapse, and duration of the platinum-free interval. Pelvis, peritoneum, pleural effusion, liver, lung, lymph nodes, and central nervous system are the most frequent sites of relapse. The standard treatment for ovarian cancer is a com- bination of surgery and chemotherapy. This retrospective study aimed to describe incidence, characteristics, outcomes and prognostic factors of patients with ovarian cancer underwent radiotherapy. RESULTS: In 47 with ovarian cancer underwent radiotherapy. Treatment modalities were radiotherapy 8- 56 Gy. After optimal treatment the authors observed complete remission in seven patients, and progression and/or metastases in 40 patients. The present study confirmed that patients with low advancement stage had better prognoses than patients with advanced disease, as confirmed by OS rates in groups TI vs. T3 (p = 0.066) and T3 vs. T4 (p = 0.066). What was in- teresting was that the disease-free survival (DFS) in the group of patients with T3 cancer was longer than in the group of patients with TI cancer. Time to marker progression (Ca 125) was longer in groups with FIGO Stage I vs. II and I vs...
Source: European Journal of Gynaecological Oncology - Category: OBGYN Tags: Eur J Gynaecol Oncol Source Type: research