A Mouse Model System for Zika Virus Infection

By Gertrud U. Rey Zika virus (ZIKV) infection causes microcephaly in newborns and is causally associated with Guillian–Barré syndrome in adults. To date, there are no drugs available to prevent or treat ZIKV infection. ZIKV vaccine research is challenging because adult immunocompetent mice are resistant to ZIKV infection and disease. The primary immunologic response to […]

Source: virology blog - June 15, 2018 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Gertrud Rey Information IFN immune evasion interferon microcephaly mouse model pathogenesis STAT2 viral virus viruses zika virus Source Type: blogs