Neural Responsiveness to Reward as an Index of Depressive Symptom Change Following Cognitive-Behavioral Therapy and SSRI Treatment.

Neural Responsiveness to Reward as an Index of Depressive Symptom Change Following Cognitive-Behavioral Therapy and SSRI Treatment. J Clin Psychiatry. 2018 Jun 12;79(4): Authors: Burkhouse KL, Gorka SM, Klumpp H, Kennedy AE, Karich S, Francis J, Ajilore O, Craske MG, Langenecker SA, Shankman SA, Hajcak G, Phan KL Abstract OBJECTIVE: Reward positivity (RewP), a neurophysiologic index of reward responsivity, is consistently reduced in participants with depression and, to a lesser extent, anxiety. It remains unknown, however, whether RewP can be altered as psychiatric symptoms change with treatment. The current study addressed this question by examining differences in RewP within patients before and after 12 weeks of treatment with a selective serotonin reuptake inhibitor (SSRI) or cognitive-behavioral therapy (CBT). We also examined the utility of RewP as a predictor of symptom change during CBT and SSRI treatment. METHODS: Participants were recruited between 2014 and 2017 and included adults with a primary DSM-5 anxiety or depressive disorder (n = 63) and healthy controls (n = 25). At baseline and 12 weeks, participants completed a monetary award task while electroencephalogram (EEG) was recorded. Between EEG sessions, patients completed CBT or SSRI treatment. RESULTS: At baseline, higher levels of depressive symptoms were associated with a more attenuated RewP. We found no significant differences between patients and healthy controls in the degree...
Source: Journal of Clinical Psychiatry - Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

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You're reading Do you worry too much? 4 Worrying Mistakes You Should Stop Making, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. Do you worry too much? According to the Anxiety and Depression American Association (ADAA) almost 40 million American adults --- one-fifth of the population--- suffer from chronic worrying and other anxiety disorders which makes them the most common mental illness in the U.S. This has lots of reasons, too much technology, insomnia and sleep deprivation, loneliness and the lack of proper commu...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: featured happiness self improvement how to be less stressed how to stop worrying Source Type: blogs
This study seeks to determine the alternations of metabolites in the bilateral anterior cingulate cortex (ACC) of CD patients with abdominal pain by using proton magnetic resonance spectroscopy (1H-MRS) to further explore the neural mechanism.MethodsSixteen CD patients with abdominal pain and 13 CD patients without abdominal pain, were recruited alongside 20 healthy controls (HCs) for this study. Clinical evaluations, including the 0–10 Visual Analogue Scale (VAS) of pain, Hospital Anxiety and Depression Scale (HADS) and Crohn's Disease Activity Index (CDAI), were evaluated prior to MR scanning. This study selected t...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
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Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
Condition:   Autologous Transplant Indication Intervention:   Other: HAD (Hospital Anxiety and Depression) scale Sponsor:   Institut de Cancérologie de la Loire Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
A $20 million gift from a longtime UCSF benefactor will help researchers zero in on brain circuitry that sets off mood disorders, such as depression and anxiety, and target personalized treatments. The donation — the second gift of this size from the Ray and Dagmar Dolby Family Fund — will establish the UCSF Dolby Center for Mood Disorders to identify brain-imaging biomarkers that could be targeted for individualized deep-brain stimulation or other treatments. What’s more, the money w ill…
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
The transition back to school each fall is challenging for many families. But some children and teens feel so much emotional distress that they may repeatedly balk at attending school or staying there — a problem known as school refusal, or school avoidance if it occurs consistently. Ways to identify school refusal and tips on responding to it quickly are described below. What is school refusal? Shifting from a more relaxed summer routine to early wake-ups, hours in class, and dreaded homework makes many students feel mildly anxious or cranky during the early weeks of a new school year. For some students, howeve...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Adolescent health Anxiety and Depression Children's Health Mental Health Parenting Source Type: blogs
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Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
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Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - Category: Infectious Diseases Tags: Clinical Science Source Type: research
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Source: Guardian Unlimited Science - Category: Science Authors: Tags: Depression Mental health Medical research Science Society UK news & wellbeing Source Type: news
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Source: Quality of Life Research - Category: Health Management Source Type: research
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