Health Economics and Clinical Decision Making in Psoriasis Health Economics and Clinical Decision Making in Psoriasis

While biological treatments for plaque psoriasis are highly effective and safe, they are also expensive. How can we prioritize their use while balancing cost-effectiveness?The British Journal of Dermatology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

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GENERAL PURPOSE: To provide information about the diagnosis and management of cutaneous psoriasis. TARGET AUDIENCE: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES: After completing this continuing education activity, the provider should be better able to: Describe the epidemiology, pathophysiology, clinical presentation, assessment, and diagnosis of the types and subtypes of psoriasis.Explain the use of topical treatments, intralesional steroids, phototherapy, conventional sys...
Source: Advances in Skin and Wound Care - Category: Dermatology Tags: FEATURES: CLINICAL MANAGEMENT EXTRA Source Type: research
This study investigated the effectiveness of adalimumab treatment in improving Work Productivity and Activity Impairment (WPAI) in patients with psoriatic arthritis (PsA) in real-world settings in Japan.MethodsThis 24-week, single-arm, postmarketing surveillance study (2014 –2017), conducted at 75 centers in Japan, enrolled adalimumab-naïve patients (paid workers, including part-time) meeting ClASsification criteria for Psoriatic ARthritis (CASPAR). The primary endpoint was improvement in overall work impairment (OWI) scores from baseline to week 24. Secondary endpo ints included changes in WPAI-PsA (OWI, absent...
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research
The objective was to investigate factors influencing patients' willingness to pay (WTP) and physician's views on the cost of therapy for two contrasted chronic diseases, chronic heart failure and psoriasis. METHODS: A cross-sectional survey was conducted in ten developing countries, using a stated WTP contingent valuation method. Multivariate analyses were performed by linear regression. RESULTS: Independent factors influencing patient WTP were income (+0.04 $PPP [purchasing power parity] in WTP per $PPP in monthly income; p 
Source: Journal of Comparative Effectiveness Research - Category: General Medicine Tags: J Comp Eff Res Source Type: research
Several skin conditions can have similar symptoms to psoriasis, and this can lead to a misdiagnosis. Learn about other conditions that look like psoriasis, and tips for getting the right diagnosis, here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Psoriasis Source Type: news
Authors: Nagai M, Imai Y, Wada Y, Kusakabe M, Yamanishi K Abstract Patients with generalized pustular psoriasis (GPP) often present with symptoms that must be differentiated from sepsis. Procalcitonin (PCT) and presepsin (P-SEP) are widely used as biomarkers for sepsis; therefore, we examined the serum PCT and P-SEP levels in patients with psoriatic diseases. The enrolled patients included 27 with psoriasis vulgaris (PV) (22 males, 5 females; mean age 47.7 years), 12 with psoriatic arthritis (PsA) (8 males, 4 females; mean age 51.3 years), and 15 with GPP (10 males, 5 females; mean age 63.7 years). The mean serum P...
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
This study compared real-world treatment patterns and healthcare costs among biologic-naive psoriasis patients initiating apremilast or biologics. METHODS: A retrospective cohort study was conducted using the Optum Clinformatics™ claims database. Patients with psoriasis were selected if they had initiated apremilast or biologics between January 1, 2014, and December 31, 2015; had 12 months of pre-index and post-index continuous enrollment in the database; and were biologic-naive. The index date was defined as the date of the first claim for apremilast or biologic and occurred between January 1, 2014, and December...
Source: Journal of Medical Economics - Category: Health Management Tags: J Med Econ Source Type: research
AbstractPurpose of ReviewThis review highlights the latest data on risankizumab, including efficacy and safety data from recent clinical trials.Recent FindingsIn multiple phase 3 clinical trials, risankizumab was shown to be safe and efficacious. Risankizumab demonstrated superior efficacy to leading active comparators for the induction and maintenance of clear skin and was shown to have a safety profile similar to other biologic therapies currently on the market.SummaryTargeted biologic medications for plaque psoriasis have provided insight into the complex immune pathways that are now understood to lead to the developmen...
Source: Current Dermatology Reports - Category: Dermatology Source Type: research
Doctors estimate that 1 to 3 percent of people with HIV also have psoriasis. In this article, we explore the link between the two, and how the treatments for HIV and psoriasis might interact.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Psoriasis Source Type: news
Review clinical reference information, guidelines, and medical news on psoriasis--including psoriasis symptoms and psoriasis treatment. Recognize psoriasis arthritis (psoriatic arthritis), scalp psoriasis, psoriasis vulgaris, and pustular psoriasis.
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Resource Center Source Type: news
Authors: Furue K, Ito T, Tsuji G, Kadono T, Furue M Abstract The excellent response of psoriasis to anti-TNF-α(TNF)/IL23/IL17A biologics implies a crucial role for the TNF/IL23/IL17 axis in developing psoriasis. In addition to the TNF/IL23/IL17 axis provided by immune cells, current evidence points to an important contribution of TNF, IL23 and IL17C produced from nonhematopoietic keratinocytes. Therefore, crosstalk between immune cells and keratinocytes forms a multilayered feed-forward loop to accelerate the TNF/IL23/IL17A axis. Many biologics have already been licensed or are under clinical trials. Given th...
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
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