Health Economics and Clinical Decision Making in Psoriasis Health Economics and Clinical Decision Making in Psoriasis

While biological treatments for plaque psoriasis are highly effective and safe, they are also expensive. How can we prioritize their use while balancing cost-effectiveness?The British Journal of Dermatology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Dermatology Journal Article Source Type: news

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Authors: Berekmeri A, Mahmood F, Wittmann M, Helliwell P Abstract INTRODUCTION: Psoriasis and psoriatic arthritis (PsA) are inflammatory immune mediated conditions which can cause considerable disability and reduced quality of life. Management can be complex as clinical heterogeneity may lead to different treatment pathways. Tofacitinib is a novel, oral janus kinase (JAK) inhibitor with proven efficacy in rheumatoid arthritis. Areas covered: This review analyses recent studies of tofacitinib in psoriatic disease treatment. The relevant literature was identified using clinicaltrials.gov, PubMed and Google Scholar. T...
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research
Publication date: Available online 17 August 2018Source: Actas Dermo-Sifiliográficas (English Edition)Author(s): A. Martin-Gorgojo, R. Martin-Brufau
Source: Actas Dermo-Sifiliograficas - Category: Dermatology Source Type: research
Treatment satisfaction is paramount to the field of dermatology. Treatment dissatisfaction directly impacts patient outcomes and health care delivery. A critical need exists for standardized, validated treatment satisfaction measures in dermatology. Comprehensive evaluation of the performance of treatment satisfaction instruments used in psoriasis is lacking. We sought to critically appraise the literature on measurement properties of treatment satisfaction instruments used in psoriasis. We performed a systematic review to identify treatment satisfaction instruments used in psoriasis and corresponding studies on their meas...
Source: Dermatology - Category: Dermatology Source Type: research
Condition:   Psoriasis Interventions:   Drug: BI 730357;   Drug: Placebo Sponsor:   Boehringer Ingelheim Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Updated Date: Aug 17, 2018 EST
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
British Journal of Dermatology,Volume 0, Issue ja, -Not available-.
Source: British Journal of Dermatology - Category: Dermatology Authors: Source Type: research
British Journal of Dermatology, EarlyView.
Source: British Journal of Dermatology - Category: Dermatology Authors: Source Type: research
This article provides a summary of the Evidence Review Group ’s review of the company’s submission, the Evidence Review Group report and the National Institute for Health and Care Excellence Appraisal Committee’s subsequent guidance issued in March 2018. The main clinical effectiveness data were derived from three well-conducted, multicentre, double-bli nd randomised controlled trials. The trials demonstrated that brodalumab statistically significantly reduced the severity of psoriasis and its impact on health-related quality of life, compared with placebo, at 12 weeks. In comparison with ustekinumab...
Source: PharmacoEconomics - Category: Health Management Source Type: research
AbstractPsoriatic arthritis (PsA) is an inflammatory arthritis that is estimated to affect approximately 30% of patients with psoriasis. Enthesitis and dactylitis, two hallmarks of PsA, are associated with radiographic peripheral/axial joint damage and severe disease. Clinical symptoms of enthesitis include tenderness, soreness, and pain at entheses on palpation, whereas dactylitis is recognized by swelling of an entire digit that is different from adjacent digits. Both ultrasound and magnetic resonance imaging can be used to diagnose enthesitis and dactylitis, especially in patients in whom symptoms may be difficult to di...
Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
CONCLUSION: In the young adult psoriasis population, substantial QoL impairments were found. Female patients, patients with high BMI or long disease duration in particular tended to experience more difficulties. These exploratory findings indicate the need for further studies in young adults to detect potential clinical predictors for severe HRQoL impairments. PMID: 30102075 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
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