Vasculitis - 2001 National Meeting Reports

Title: Vasculitis - 2001 National Meeting ReportsCategory: Doctor's&Expert's views on SymptomsCreated: 11/24/2001 2:59:00 PMLast Editorial Review: 6/13/2018 2:55:10 PM
Source: MedicineNet Arthritis General - Category: Rheumatology Source Type: news

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te D, Alpay H Abstract Gökçe İ, Altuntaş Ü, Filinte D, Alpay H. Polyarteritis nodosa in case of familial Mediterranean fever. Turk J Pediatr 2018; 60: 326-330. Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurrent self-limited attacks of fever accompanied by peritonitis, pleuritis, and arthritis. Protracted febrile myalgia syndrome (PFMS) is a rare form of vasculitic disease which is an uncommon dramatic manifestation of FMF, characterized by severe crippling myalgia and high fever. Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis affectin...
Source: The Turkish Journal of Pediatrics - Category: Pediatrics Authors: Tags: Turk J Pediatr Source Type: research
Conditions:   Rheumatoid Arthritis;   Systemic Lupus;   Sjögren Syndrome;   Systemic Vasculitis;   Spondyloarthritis Interventions:   Biological: 13-valent pneumococcal conjugate vaccine;   Biological: 23-valent pneumococcal polysaccharide vaccine Sponsor:   Region Skane Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Paola Caruso, Rita MorettiNeurology India 2018 66(6):1619-1628 Behçet's disease (BD) is a multisystemic vasculitis disorder of almost unknown etiology, which involves small and large vessels and affects both veins and arteries. BD is characterized by recurrent oral aphthae (the main and most recurrent symptoms), genital ulcers, variable skin lesions, arthritis, uveitis, and thrombophlebitis. Other reported symptoms concern the involvement of the gastrointestinal and the central nervous system. Neuro-Behçet's disease (NBD) is one of the main causes of long-term morbidity and mortality, making its prompt r...
Source: Neurology India - Category: Neurology Authors: Source Type: research
The epichaperome is a new cancer target defined, in part, by changes in the interaction strength between chaperone and co-chaperone proteins to form stable hyperconnected networks that support oncoprotein stability and are vital for tumor survival (Nature 2016, Nature Rev Cancer 2018 and Nature Med 2018). Cancers with this altered chaperone configuration may become susceptible to drugs that target the epichaperome, such as the inhibitor PU-H71. We have developed a novel flow cytometry-based test, the PU-FITC binding assay, to evaluate epichaperome levels at the single cell level and identify patients who are most likely to...
Source: Blood - Category: Hematology Authors: Tags: 616. Acute Myeloid Leukemia: Novel Therapy, excluding Transplantation: Poster I Source Type: research
Introduction: A subset of patients with MDS and related myeloid disorders present with concomitant autoimmune rheumatological diseases (AIRD); however the prevalence ranges from 10-48% based on limited literature. Further, use of immunosuppressive agents in AIRD patients could confound the secondary diagnosis of MDS and in some cases cause it (therapy-related myeloid neoplasm; t-MN). The prevalence of cytopenia in AIRD patients is unknown and the genetic characteristics of MDS patients with concomitant AIRD have not been described. Hence, we interrogated two large multi-institutional databases -Royal Adelaide Hospital Rheu...
Source: Blood - Category: Hematology Authors: Tags: 636. Myelodysplastic Syndromes-Basic and Translational Studies: Poster II Source Type: research
Conclusions: Diagnosis can be challenging in patients presenting with pleural disease as the first manifestation of a CTD. We recommend a multidisciplinary approach in management.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interventional Pulmonology Source Type: research
ConclusionS100A12 as a highly expressed mediator of sterile inflammation in KD can activate coronary artery endothelial cells in an IL ‐1β‐dependent manner. Our data provide new mechanistic insights on the contribution of S100A12 and IL‐1β in disease pathogenesis and support current IL‐1 targeting studies in KD.This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Full Length Source Type: research
Henoch-Schonlein purpura (HSP) is a small vessel vasculitis that is characterized by non-thrombocytopenic purpura, abdominal pain, arthritis, and glomerulonephritis. Typically, HSP is self-limited requiring on...
Source: Pediatric Rheumatology - Category: Rheumatology Authors: Tags: Research article Source Type: research
ConclusionsThis study suggests that disease status at three and six months may predict the risk of long ‐term mortality and ESRF in AAV, and that these time points may be valid end‐points for induction trials in AAV. These results need to be validated in a larger dataset.This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: Full Length Source Type: research
AbstractWe cared for a woman with sero-positive rheumatoid arthritis (RA), in clinical remission on oral methotrexate (MTX) and hydroxychloroquine, who wished to donate a kidney to a brother with end-stage renal disease (ESRD). We could find scant literature about this unusual clinical circumstance, and therefore review pertinent aspects of renal disease in RA, perioperative medical management, maintenance of disease remission, outcomes for RA patients who have donated kidneys, and relevant ethical issues. Renal complications in RA are not uncommon, with as many as 50% of patients at risk of reduced eGFR. This reflects ant...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
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