Drug Withdrawn - Vioxx, A Perspective After National Arthritis Meeting

Title: Drug Withdrawn - Vioxx, A Perspective After National Arthritis MeetingCategory: Doctor's&Expert's views on SymptomsCreated: 11/1/2004 12:00:00 AMLast Editorial Review: 6/13/2018 2:55:10 PM
Source: MedicineNet Arthritis General - Category: Rheumatology Source Type: news

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Review clinical reference information, guidelines, and medical news on psoriasis--including psoriasis symptoms and psoriasis treatment. Recognize psoriasis arthritis (psoriatic arthritis), scalp psoriasis, psoriasis vulgaris, and pustular psoriasis.
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Resource Center Source Type: news
A belated Happy New Year to my fellow advocates! Here’s your first update for 2019 on what the rheumatology community should know is going on in Washington, D.C., right now. Current Climate On Jan. 3, the 116th Congress gaveled into session with Democrats in control of the House of Representatives and Republicans still the majority in the... [Read More]
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: American College of Rheumatology Legislation & Advocacy 2019 advocacy fronts D.C. update DoD arthritis research E/M billing codes International Pricing Index (IPI) model step therapy Source Type: research
Authors: Furue K, Ito T, Tsuji G, Kadono T, Furue M Abstract The excellent response of psoriasis to anti-TNF-α(TNF)/IL23/IL17A biologics implies a crucial role for the TNF/IL23/IL17 axis in developing psoriasis. In addition to the TNF/IL23/IL17 axis provided by immune cells, current evidence points to an important contribution of TNF, IL23 and IL17C produced from nonhematopoietic keratinocytes. Therefore, crosstalk between immune cells and keratinocytes forms a multilayered feed-forward loop to accelerate the TNF/IL23/IL17A axis. Many biologics have already been licensed or are under clinical trials. Given th...
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
ConclusionThis molecular mechanism of the investigation confirmed the clinical efficacy of Kashayams in preventing the progression of RA and gave an intuition of the scientific validation of Kashayams, an Ayurvedic classical medicine.
Source: Journal of Ayurveda and Integrative Medicine - Category: Complementary Medicine Source Type: research
Conclusion: Shikonin has anti-inflammatory effects on CIA. Shikonin treatment can inhibit Th17 cytokines expression and induce Treg responses through inhibiting the activation of TLR4/MyD88 pathway. PMID: 30643526 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Abstract An eleven-year-old boy presented with fever and hip pain, with limited mobility of the right side of the hip. Computed tomography scan revealed an increased volume of the right coxo-femoral joint, requiring surgical drainage of purulent secretion, from which Salmonella enterica was isolated. After four weeks of treatment with third-generation cephalosporin, he was discharged with a favorable evolution. Invasive disease caused by Salmonella spp represents a small proportion of salmonellosis cases, although it is responsible for greater rates of hospitalization, morbidity and mortality. Children under 5 years, elder...
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
In this study, the efficacy of clarithromycin in protecting against pulmonary fibrosis was investigated in the rat model for methotrexate-induced pulmonary fibrosis. Material and methods: A total of 30 female rats were divided into three groups. Group I was administered intraperitoneal and intragastric saline; group II was administered oral 3 mg/kg methotrexate; and group III was administered oral 3 mg/kg methotrexate + intraperitoneal 200 mg/kg clarithromycin for 28 days. Histopathological analyses of the lung tissues were performed under light microscopy. Results: Normal histopathological changes were observed in t...
Source: Polish Journal of Cardio-Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Tags: Kardiochir Torakochirurgia Pol Source Type: research
In conclusion… It’s true: medical myths die hard. In fact, some seem immortal. One could argue that’s as it should be. After all, yesterday’s medical myth is only one discovery away from becoming tomorrow’s medical fact. Still, when the evidence is compelling, I think we’d be better off letting go of what’s been disproven, give more credence to evidence than folklore, and keep an open mind — just in case the evidence changes. When my patients tell me they can predict the weather by how their joints feel, I believe them. It’s hard to discount it when so many people noti...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Arthritis Bones and joints Health Source Type: blogs
RHEUMATOID arthritis symptoms include joint pain, inflammation, and restricted movement. But the condition, which affects about 400,000 people in the UK, could also cause this feeling in your eyes - are you at risk?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
ConclusionsIn Mexican patients from the tofacitinib global RA program, tofacitinib efficacy was demonstrated up to Month 12 in Phase 3 studies and Month 36 in the LTE study, with a safety profile consistent with tofacitinib global population.ResumenObjetivosTofacitinib es un inhibidor de la cinasa Janus para el tratamiento de la artritis reumatoide (AR). Se evaluaron la eficacia y la seguridad de tofacitinib en pacientes mexicanos a partir de los estudios fase 3 y de extensión a largo plazo (ELP) de AR.Mèc)todosDatos de pacientes mexicanos con AR y respuesta inadecuada a fármacos antirreumáticos...
Source: Reumatologia Clinica - Category: Rheumatology Source Type: research
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