That Huge Mediterranean Diet Study Was Flawed. But Was It Wrong?

A highly publicized trial in Spain found that the Mediterranean diet protects against heart disease. Now the original work has been retracted and re-analyzed, with the same result.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Diet and Nutrition Heart Nuts Olive Oil Statistics New England Journal of Medicine Spain Mediterranean diet Source Type: news

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This study explored the effects of probucol on atherosclerotic plaques and soluble thrombomodulin in patients with coronary heart disease (CHD). Five hundred and eighty-three patients with CHD who were admitted to Jining First People's Hospital from February 2013 to February 2014. A total of 300 of them received conventional treatment, and were assigned to the control group, while the remaining 283 patients were treated with probucol in addition to the conventional treatment, and were assigned to the observation group. A retrospective analysis was performed on the total cholesterol levels, atherosclerotic plaque sizes, and...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Zhang H, Niu H, Yuan X, Chang J, Wang X Abstract Effects of trimetazidine combined with berberine on endothelial function of patients with coronary heart disease combined with primary hypertension (CCP) were investigated. A total of 68 patients with CCP were selected from July 2014 to August 2016 to serve as observation group. At the same time, 68 healthy people were also selected to serve as control group (physiological saline). Expression of endothelial nitric oxide synthase (eNOS) mRNA in the blood samples of the observation and control groups before and after treatment was determined by RT-PCR. Levels ...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Li L, Hao J, Qu S, Fang Y Abstract Computed tomography angiography (CTA) is an efficient method for the diagnosis of heart disease. However, few contemporary studies have evaluated the prognostic value of three-dimensional (3D)-CTA for patients with acute coronary artery disease. The aim of the present study was to investigate the diagnostic value of 3D-CTA for patients with acute coronary artery disease. A total of 136 patients with suspected acute coronary artery disease were recruited and received conventional coronary angiography (CCA) and 3D-CTA. 3D-CTA was used to assess calcified plaques in the coro...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In this study, medical fles of all pediatric patients admitted to the Mofd and Imam Hossein children’s hospitals with the diagnosisof AIS from 2001 to 2011 and 2011 to 2016, respectively, were evaluated. Identifed risk factors of AIS were categorized as arteriopathies, cardiac disorders (CDs), infection, acute head ‑and‑neck disorders, acute systemic conditions, chronic systemic conditions, prothrombotic states, chronichead ‑and‑neck disorders, atherosclerosis‑related RFs, and others.Results:In this study, 61 patients were evaluated. Mean (standard deviation) age of the patients was 5.1 (3.9) years. About 6...
Source: International Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Authors: Han B, Wang Q Abstract Pulmonary hypertension due to left heart disease (PH-LHD) is caused by left ventricular (LV) systolic and/or diastolic dysfunction and left heart valve disease. LV diseases lead to left ventricular filling pressure increases, pulmonary venous obstruction and pulmonary venous pressure increases, and thus to secondary PH. Exercise tolerance is lower and fatality rates are higher in patients with PH-LHD than those in subjects with normal pulmonary arterial pressure. In spite of the progress in the study of the mechanisms of PH-LHD in recent years, no specific treatment is currently avai...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
ConclusionIntravenous iodinated contrast medium in children with congenital heart disease caused transient thyroid-stimulating hormone decrease 48  h after CT, with thyroid-stimulating hormone returning to normal range at discharge.
Source: Pediatric Radiology - Category: Radiology Source Type: research
Patients with congenital heart disease with a pressure-overloaded right ventricle can develop liver disease and would benefit from non-invasive diagnostic modalities such as ultrasound shear wave elastography (US SWE). We sought to investigate the ability of US SWE to measure dynamic changes in liver stiffness with an acute fluid bolus in an animal model. Three piglets underwent surgical intervention to create a pressure-overloaded right ventricle and, 12 wk later, underwent US SWE, both pre- and post-intravenous infusion of a saline bolus.
Source: Ultrasound in Medicine and Biology - Category: Radiology Authors: Tags: Technical Note Source Type: research
Childhood obesity affects over 12.5 million children in the US [1]. Obese children are more likely to have poor metabolic profiles compared to their normal-weight peers [2,3]. Over their lifetimes, obese children are also at greater risk of chronic obesity, diabetes, heart disease, and cancer [4,5]. Childhood is an important stage during which to intervene, as it is a sensitive period for developing eating, physical activity, and screen time patterns [6,7]. The United States Department of Agriculture recommends that children consume 1-2 cups of fruits and 1-3 cups of vegetables daily, but only 40% of children meet the frui...
Source: Patient Education and Counseling - Category: International Medicine & Public Health Authors: Source Type: research
Variations in coronary anatomy are common and may relate to the position of the coronary ostium relative to the aortic sinus, the angle of coronary take off, or the course of the coronary arterial branches. Several classification systems have been proposed. However, they all lack a simple rationale that is applicable irrespective of the relative position of the great arteries, as well as in bicuspid aortic valves. Here, we present a modification of a relatively simple system introduced in the early eighties, designated the “The Leiden Convention“.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
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