More US Kids Unvaccinated in States That Allow Non-Medical Exemptions More US Kids Unvaccinated in States That Allow Non-Medical Exemptions

A growing number of children are missing out on recommended vaccinations in states that permit parents to skip inoculations due to their personal beliefs even when there's no medical reason kids can't be vaccinated, a U.S. study suggests.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Pediatrics News Source Type: news

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Publication date: 17–23 November 2018Source: The Lancet, Volume 392, Issue 10160Author(s): The Lancet
Source: The Lancet - Category: General Medicine Source Type: research
Rhinosinusitis affects many pediatric patients as well as 1 in 6 adults in any given year, resulting in ambulatory care, pediatric, and emergency department visits. Uncomplicated rhinosinusitis requires no imaging or testing and does not require antibiotic treatment. Using strict clinical diagnostic criteria may minimize unnecessary antibiotics. When indicated, amoxicillin with or without clavulanate for 5 to 10  days remains the first-line antibiotic, despite increasing incidence of staphylococcal sinusitis in the post-pneumococcal conjugate vaccine era. Emergency providers also need to recognize atypical cases in wh...
Source: Emergency Medicine Clinics of North America - Category: Emergency Medicine Authors: Source Type: research
Authors: Blanchard E, Piquet J, Piperno D, Pinet C, Stach B, Roche N PMID: 30429091 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
We describe here that pre-exposure with a live virus generated via a A/WSN/1933(H1N1) reverse genetics system resulted in a significant reduction of viral shedding from pigs exposed to either a swine H1N1 virus or a swine H3N2 virus. At 3-day post challenge (DPC), approximately 1 log and 1.5 logs reductions of viral shedding were observed in the swine H1N1- and H3N2-challenged vaccinated pigs when compared to unvaccinated animals. A further decline in viral load was observed at 5 DPC where viral shedding was decreased by greater than 3 logs in vaccinated pigs receiving either the H1N1 or H3N2 virus challenge. Although the ...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Publication date: March 2019Source: Fish &Shellfish Immunology, Volume 86Author(s): Simon Menanteau-Ledouble, Frouke van Sorgen, Rui Alexandre Gonçalves, Mansour El-MatbouliAbstractImmunostimulatory feed supplements are an increasingly common feature of aquaculture management and their benefit has been confirmed for a wide area of products. However, these investigations have often focused on the benefit of these supplements on the innate immune system. In the current project, we investigated a mixture of two commercial feed supplements (Biotronic® Top 3 and Levabon® Aquagrow E) with a known protective ef...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
The objectives of this study were to identify the major adhesin in Omps that plays the essential role in adhesion of V. harveyi to the host cells, and to assess the potential of this adhesin as a vaccine candidate for V. harveyi infection. We observed that pathogenic V. harveyi adhered to the surface of grouper embryonic cells (GEM cells) and induced apoptosis of them. Native Omps were extracted from nine different V. harveyi strains, and five common Omp bands were isolated by SDS-PAGE analysis. Western blot analysis and an anti-native Omp antibodies blocking assay indicated that one strong and several weak immunoreactivit...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
This article aims to evaluate a three-stage PEG-Salt aqueous two-phase extraction (ATPE) system to purify foot-and-mouth disease virus (FMDV). Unique separation efficiencies were obtained by selecting phase-forming salt and varying the molecular weight (MW) of PEG and the pH value by using neutral salt additives. Improving the purity of FMDV and removing the phase-forming polymer were performed by multi-stage ATPE system. Results revealed that the partition coefficient (K) of FMDV in single-stage ATPE did not linearly increase with the MW of PEG. The highest K value and recovery of FMDV were 98.9% and 107.69, respectively,...
Source: Process Biochemistry - Category: Biochemistry Source Type: research
CONCLUSIONS: PHDs on remote islands highly value the validity and deployment needs of PHDs, while PHDs in close proximity to private clinics or hospitals give a low score. This suggests that there is a need to more efficiently deploy PHDs depending on local characteristics and the presence or absence of nearby private medical clinics and hospitals. PMID: 30424679 [PubMed - in process]
Source: Rural and Remote Health - Category: Rural Health Tags: Rural Remote Health Source Type: research
ConclusionsTST and IGRA have a low agreement. Both tests should be included in the strategy to diagnose LTBI prior to biologic therapy in IMID patients.
Source: The Egyptian Rheumatologist - Category: Rheumatology Source Type: research
Condition:   Influenza Interventions:   Biological: Quadrivalent influenza vaccine;   Biological: Trivalent influenza vaccine A;   Biological: Trivalent influenza vaccine B Sponsor:   Shanghai Institute Of Biological Products Not yet recruiting
Source: - Category: Research Source Type: clinical trials
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