Evaluation of XRCC1 Gene Polymorphism as a Biomarker in Head and Neck Cancer Patients Undergoing Chemoradiation Therapy.
CONCLUSIONS: Polymorphic variant XRCC1 HNSCC patients treated with CCRT have significantly increased acute radiation morbidities and may have a trend toward better PFS in comparison with the wild variant. PMID: 29893275 [PubMed - in process]
Illingworth Research Group Ltd are coordinating aphase I study to investigate a potential new drug, K1-70, developed to treat patients who have Graves’ disease, thyroid cancer, and patients who would benefit from controlling thyroid stimulating hormone receptor activity.Illingworth Research Group Ltd need a further 8 patients with Graves’ disease to complete this study. For more information, please contact:• Volunteer Services team at the Medicines Evaluation Unit on 0800 655 6553 and quote study MEU 15/304• Recru...
Conclusions: Our results suggest that multiple organ failure should not be used as a criterion for excluding a patient with a hematologic malignancy from admission to the ICU.
In conclusion, these results suggest that HA–CL and SAP had anti-inflammatory activity and acted in combination to accelerate wound healing. Therefore, LYO HA–CL – SAP could be a potential adjuvant in nasal anti-inflammatory formulations.Graphical abstract
Publication date: March 2019Source: Biomedicine &Pharmacotherapy, Volume 111Author(s): Guanghui Wang, Bin Shi, Yunong Fu, Shasha Zhao, Kai Qu, Qingbo Guo, Ke Li, Junjun SheAbstractGastric cancer (GC) has been an increasingly serious problem in public health. However, there is still a lack of efficient approach to diagnosis and treatment in time, especially in the field of targeted therapy. Increasing evidences demonstrated that DNA methylation plays an essential role in tumorigenesis and progression of GC. Thus the present study aims to identify DNA methylation-based prognostic biomarkers in GC. Two methylation array d...
Pooja Ghatalia, Chad H. Smith, Arthur Winer, Jiangtao Gou, Lesli A. Kiedrowski, Michael Slifker, Patricia D. Saltzberg, Nicole Bubes, Fern M. Anari, Vineela Kasireddy, Asya Varshavsky, Yang Liu, Eric A. Ross, Wafik S. El-Deiry
Hyeong Dong Yuk, Chang Wook Jeong, Cheol Kwak, Hyeon Hoe Kim, Ja Hyeon Ku
Cancer therapy decisions are often made according to the histopathological-molecular profile of tumor tissue obtained from surgery or biopsy. It has been shown that tumor profiles change with time and treatment, and that tumor tissue is heterogeneous. Thus, other approaches that are easily accessible and less invasive than surgery or biopsy to monitor responses to treatment and predict relapses are urgently needed. In the last few years, the term “liquid biopsies” has been introduced to represent multifunctional circulating biomarkers in the peripheral blood and other physiological fluids of patients with cance...
PROSTATE cancer symptoms can be difficult to spot in its early stages, but usually affect the way you pass urine. You could be at risk of the disease ’s signs and symptoms if you use the toilet more often - how many times do you go for a wee every day?
I am a firm believer in the ability of music to help people express their emotions, hopes and fears, making their medical conditions more tolerable.
The E.P.A. warns that radon causes cancer. But some tourists head to mines in Montana to soak it up.
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