Medical News Today: How can disc desiccation be treated?

The bones in the back have sponge-like discs between them. These discs can become dehydrated and lose flexibility, often as people age, resulting in desiccation. Treatment, that can include at-home therapy, depends on the severity of the desiccation, which can cause stiffness in the back and pain. Learn more here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Back Pain Source Type: news

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ConclusionsIn approximately 90% of patients, bony fusion is accomplished one year after ACDF. As there is no generally accepted definition of bony fusion, different measuring techniques cannot be compared to a gold standard and it is impossible to determine the most accurate method. Variations in study design hamper conclusions on optimising the rate of bony fusion by choice of material and/or additives. Insufficient attention is paid to correlation between bony fusion and clinical outcome.Graphical abstractThese slides can be retrieved from electronic supplementary material.
Source: European Spine Journal - Category: Orthopaedics Source Type: research
AbstractInflammation is the body ’s response to injury and infection, involving a complex biological response of the somatosensory, immune, autonomic, and vascular systems. Inflammatory mediators such as prostaglandin, proinflammatory cytokines, and chemokines induce pain via direct activation of nociceptors, the primary sensory neurons that detect noxious stimuli. Neurogenic inflammation is triggered by nerve activation and results in neuropeptide release and rapid plasma extravasation and edema, contributing to pain conditions such as headache. Neuroinflammation is a localized inflammation in the peripheral nervous...
Source: Journal of Anesthesia - Category: Anesthesiology Source Type: research
ConclusionCongenital morphological disorders may occur at the lower cervical spine and cervicothoracic junction, and they can involve the vertebral body as well as the posterior arch. We reported three cases of uncommon malformations, with a unique Y- and S-shaped laminar pattern.
Source: Surgical and Radiologic Anatomy - Category: Anatomy Source Type: research
Publication date: Available online 15 November 2018Source: NeuronAuthor(s): Arnab Barik, James Hunter Thompson, Mathew Seltzer, Nima Ghitani, Alexander T. CheslerSummaryResponse to danger needs to be rapid and appropriate. In humans, nocifensive behaviors often precede conscious pain perception. Much is known about local spinal cord circuits for simple reflexive responses, but the mechanisms underlying more complex behaviors remain poorly understood. We now describe a brainstem circuit that controls escape responses to select noxious stimuli. Tracing experiments characterized a highly interconnected excitatory circuit invo...
Source: Neuron - Category: Neuroscience Source Type: research
Nevro (NYSE:NVRO) is seeking a reversal and remand for spinal cord stimulation patent infringement case against Boston Scientific (NYSE:BSX) that was ruled on this summer. A legal firm representing the company filed a brief this week seeking to overturn a decision from this summer which found a number of patent claims invalid as indefinite. In mid-July, a federal judge in California issued a mixed ruling in the ongoing case, finding that six claims in three of the Nevro patents are eligible but also that Boston’s SCS devices don’t infringe those claims (Boston doesn’t have a compe...
Source: Mass Device - Category: Medical Devices Authors: Tags: Legal News Pain Management Patent Infringement Boston Scientific Nevro Corp. Source Type: news
In this study, we determined the role of the CXCL10-CXCR3 axis in NP using a well-established CCI model. CCI significantly induced mechanical allodynia and thermal hyperalgesia. Following the pain course, a significant increase of CXCL10 and CXCR3 in both dorsal root ganglion (DRG) neurons and spinal cord (SC) neurons was detected in rats. Furthermore, intrathecal injection of CXCR3 inhibitor AMG487 was found to attenuate pain hypersensitivity in a dose-dependent manner in CCI. The expression of p-ERK was also depressed after intrathecal injection of AMG487 associated with a significant laxation of hyperalgesia, which demo...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
This study retrospectively investigated the efficacy of the ESP block in pain management after lumbar spinal surgery. Methods: Patients who underwent lumbar spinal surgery in 2017 were enrolled in the study. Those who underwent secondary surgery with local anesthesia other than the ESP block were excluded. The primary outcome was the Numerical Rating Scale (NRS) pain score at various time points until the morning of postoperative day 2. The secondary outcomes were the amount of intravenous fentanyl administered during the first 24 hours following the surgery and the number of patients with complaints of complications s...
Source: Asian Spine Journal - Category: Orthopaedics Tags: Asian Spine J Source Type: research
No abstract available
Source: The Back Letter - Category: Orthopaedics Tags: Articles Source Type: research
No abstract available
Source: The Back Letter - Category: Orthopaedics Tags: Articles Source Type: research
No abstract available
Source: The Back Letter - Category: Orthopaedics Tags: Articles Source Type: research
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