Five-year outcome and predictors of success after second-generation cryoballoon ablation for treatment of symptomatic atrial fibrillation.
CONCLUSIONS: Sinus rhythm was maintained in a substantial proportion of patients even 5 years after CB-Adv ablation. Patients with a non-enlarged left atrium without diabetes had the best outcome. PMID: 29887425 [PubMed - in process]
Conclusion In a large US-based outpatient registry, we found that a quarter of adults with T2D had a diagnosis of HF, which was predominantly HFpEF. Although certain T2D medication use in patients with HF appeared consistent with evidence (less use of thiazolidinediones), others appeared contrary to evidence (less use of metformin and SGLT2 inhibitors).
This study explored the difference in the occurrence of spontaneous AA after AFl ablation as a function of the patient's presenting rhythm on the day of the AFl ablation. A retrospective study of consecutive patients who underwent AFl ablation at Baylor University Medical Center at Dallas was performed. A total of 188 subjects were included; 50% (94) presented in AFl (Group AFl) on the day of the ablation procedure and 94 presented in sinus rhythm (SR; Group SR). Group AFl patients were older (P
ConclusionThis paper presents a summary of key clinical cardiology trials during the past year and should be of practical value to both clinicians and cardiology researchers.
The negative impact of atrial fibrillation (AF) on the morbidity, mortality and well-being of patients is well established . Together with the increasing incidence due to the ageing of the population and the increased prevalence of risk factors such as diabetes and hypertension, this has made AF a major clinical problem [1,2]. Current AF management remains suboptimal, with numerous translational challenges that need to be overcome in order to develop more effective, personalized therapeutic strategies .
Both heart failure (HF) and atrial fibrillation (AF) affect millions of people worldwide . An increasing number of HF patients have preserved ejection fraction (HFpEF) and both AF and HFpEF are heterogeneous diseases with regard to symptomatology, associated comorbidities, and prognosis. The two are inextricably linked to each other, since both are related to increasing age, hypertension and diabetes, and may predispose to one other . Separately, both diseases have a negative impact on the life expectancy of patients suffering from one of those diseases.
In this issue of the International Journal of Cardiology, Mancusi et al.  evaluated the effect of left atrial (LA) dilatation independently of target organ damage (TOD) on cardiovascular (CV) outcomes in young to middle-aged hypertensive patients from the Campania Salute Network (CSN). Overall, 5844 young adult hypertensive patients (mean age 50 ± 9 years, 41% women, 8% with diabetes) without prevalent CV disease or atrial fibrillation (AF) and with normal (>50%) left ventricular (LV) ejection fraction were included.
In a recent article in The American Journal of Cardiology, Magnussen C et al.1 highlighted substantial sex differences in cardiovascular risk factors distribution, comorbidities, symptom burden and cardiac function among individuals with atrial fibrillation (AF). There has been strong evidence for sex heterogeneity in the association of AF with CAD, MI, GAD, diabetes, HDL-C, and triglycerides in aged-adjusted model. Statistically significant sex by AF interactions were observed for IVSD, LADI, and MI in the multivariable-adjusted model.
CONCLUSION: hFABP, tachycardia, hypotension and DM were identified as the major independent determinants of complications development in patients with pulmonary embolism and may be used in combination as the bedside simple predictive ROCky score for early risk stratification in intermediate-risk group. PMID: 29866478 [PubMed - as supplied by publisher]
ncü N, Zoghi M Abstract OBJECTIVE: The aim of this study was to determine the baseline clinical characteristics and the cardiovascular drug usage of patients aged ≥80 years who were admitted to cardiology clinics and to compare the cardiovascular disease and risk factors with patients aged 65-79 years who participated in the Epidemiology of Cardiovascular Disease in Elderly Turkish Population (ELDER-TURK) study. METHODS: The ELDER-TURK study included 5694 patients aged over 65 years who were followed up at cardiology clinics between March 2015 and December 2015. The prevalence of cardiovascular diseas...
Obesity is a key factor for cardiovascular diseases and complications. Obesity is associated with hypertension, dyslipidemia and type II diabetes, which are the major predictors of cardiovascular disease in the future. It predisposes for atrial fibrillation, heart failure, sudden cardiac death, renal disease and ischemic stroke that are the main causes of cardiovascular hospitalization and mortality. As obesity and the cardiovascular effects on the vessels and the heart start early in life, even from childhood, it is important for health policies to prevent obesity very early before the disease manifestation emerge. Key ro...