Five-year outcome and predictors of success after second-generation cryoballoon ablation for treatment of symptomatic atrial fibrillation.

CONCLUSIONS: Sinus rhythm was maintained in a substantial proportion of patients even 5 years after CB-Adv ablation. Patients with a non-enlarged left atrium without diabetes had the best outcome. PMID: 29887425 [PubMed - in process]
Source: Adv Data - Category: Epidemiology Authors: Tags: Int J Cardiol Source Type: research

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AbstractPurpose of ReviewTo evaluate the most recent evolutions in the field of single photon emission computed tomography (SPECT) nuclear cardiac imaging (NCI), particularly regarding the influence of stress protocol specifics on test accuracy.Recent FindingsThe substantial improvement in both software and hardware SPECT settings may allow a drastic redefinition of the acquisition parameters, with a radical reduction of scanning time. Moreover, recent evidence has identified novel (contra)-indications to the different cardiac stressors, defining the categories of patients in which a specific stressor is most appropriate.S...
Source: Current Cardiovascular Imaging Reports - Category: Radiology Source Type: research
Globalization reached healthcare big time: a French patient can easily ask a Belgian company to sequence the DNA of his tumor tissue, then convince a Swiss pharma company to sign them up for a relevant clinical trial on a Spanish island. Not only that but also the recent controversies around gene editing in babies in China, as well as the operation of direct-to-consumer genetic testing companies, the online medication scene, health technology companies expanding their services to other countries highlight the need for a global “FDA” day by day. We are not waiting for regulators The availability of know-how, raw...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine Policy Makers 3d printing diabetes diabetes management digital health digital health companies fda genetics global globalization health policy Healthcare regulation regulations Source Type: blogs
Authors: Plasek J, Taborsky M Abstract Atrial fibrillation is the most common arrhythmia and as such, it has become a significant public health issue due to its impact on patient morbidity and mortality. The prevalence of atrial fibrillation (AF) almost doubled in the last decade, being currently 2% in unselected patient populations. Its occurrence varies with age (present in almost 20% of octogenarians) and concomitant diseases. The most prevalent concomitant diseases are hypertension, diabetes, heart failure, renal failure, and cognitive decline. Cognitive decline or stroke may be actually the first manifestation...
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - Category: Biomedical Science Tags: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Source Type: research
Smart belt for weight loss, spider-like walking car, terrifying Robo-Sharks, IoT cat toilet, the real version of the monolith from Space Odyssey: the world’s most famous tech circus brings the superlatives of innovation to Las Vegas every year. Here, we sorted out the most exciting, the less useful or the outright dumbest health technology from CES 2019. The year of the solar cow What do power banks and cows have in common? The 2019 CES Innovation Award, actually. It’s a brilliant project of a South Korean solar energy company, Yolk, having partnered with a Kenyan educational institution, to keep children at s...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine ces CES 2019 digital digital health digital health tech gadgets health technology health trends Innovation smartwatch summit wearables Source Type: blogs
In a blog post last week, I shared an excerpt from the new book that Paul Cerrato and I just completed,The Transformative Power of Mobile Medicine. Here is a second excerpt from Chapter 3,  “Exploring the Strengths and Weaknesses of Mobile Health Apps.”Even patients who are fully engaged in their own care still need access to medical apps they can trust. The IQVIA Institute for Human Data Science has performed a detailed analysis of the clinical evidence supporting mobile health apps, rating their maturity and relative quality. Its rating scale places a single observational study near the bottom of th...
Source: Life as a Healthcare CIO - Category: Information Technology Source Type: blogs
Calcium/calmodulin-dependent protein kinase II (CaMKII) is upregulated in diabetes and significantly contributes to cardiac remodeling with increased risk of cardiac arrhythmias. Diabetes is frequently associated with atrial fibrillation, coronary artery disease, and heart failure, which may further enhance CaMKII. Activation of CaMKII occurs downstream of neurohormonal stimulation (e.g. via G-protein coupled receptors) and involve various posttranslational modifications including autophosphorylation, oxidation, S-nitrosylation and O-GlcNAcylation.
Source: Journal of Molecular and Cellular Cardiology - Category: Cytology Authors: Tags: Review article Source Type: research
Edwin A. Homan, Michael V. Reyes, Kathleen T. Hickey, John P. Morrow
Source: Frontiers in Physiology - Category: Physiology Source Type: research
ConclusionWe confirmed associations of several risk factors with HF in this large population ‐based cohort across age and sex subgroups. Mainly modifiable risk factors and comorbidities are strongly associated with incident HF, highlighting the importance of preventive strategies targeting such risk factors for HF.
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Research Article Source Type: research
ConclusionsIncidence rates of IS/TE, mortality and bleeding increased with worsening eGFR. Worsening eGFR was an independent predictor of IS/TE and bleeding, and a better predictor of IS/TE than renal impairment in AF. We were able to identify predictors of worsening renal function, which may help to tag patients needing regular FU for appropriate adaptation of antithrombotic therapy.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Source: Notes from Dr. RW - Category: Internal Medicine Tags: cardiovascular endocrinology Source Type: blogs
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