Diagnostic Accuracy of Magnifying Endoscopy with Narrow Band Imaging and Its Diagnostic Value for Invasion Depth Staging in Esophageal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.
Conclusions: ME-NBI provides a high diagnostic rate in evaluating the esophagus to diagnose squamous cell carcinoma. In the differentiation for invasion depth staging, ME-NBI was demonstrated to be superior to white light endoscopy and had a similar diagnostic rate compared with HF-EUS. However, HF-EUS had high positive likelihood values for invasion depth staging, suggesting that HF-EUS is a reliable method for confirming invasion depth staging. PMID: 29888281 [PubMed - in process]
Authors: Fleischmann C, Messmann H Abstract Esophageal squamous cell carcinoma (ESCC) remains the most common esophageal cancer in the world, though a rising incidence of esophageal adenocarcinoma could be seen during the last decade in the western world. There are several known risk factors for ESCC, such as smoking, alcohol consumption, radiation or others. As there is a risk of lymph node metastasis already in early stages, early endoscopic detection is crucial for curative endoscopic treatment options. Therefore, newest techniqual improvements such as enhancement techniques or virtual chromoendoscopy are helpfu...
Esophageal large-cell neuroendocrine carcinoma (NEC) is a rare malignant tumor that is characterized by high-grade malignancy and a poor prognosis. However, the rarity of esophageal NEC has prevented the development of an established treatment, and no reports have described a discrepancy in the effectiveness of cisplatin plus irinotecan between primary and metastatic lesions. A 43-year-old Japanese man was referred to our hospital with refractory epigastralgia. A previous gastrointestinal endoscopy had revealed a 50-mm type 2 tumor in the abdominal esophagus. The pathological findings indicated poorly differentiated squamo...
CONCLUSIONS: Endoscopic assessment allows a rather accurate estimation of invasion depth of early esophageal cancer. To determine the final treatment modality however the final histological staging obtained by endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) is crucial. PMID: 29795069 [PubMed - as supplied by publisher]
To evaluate benefits and limitations of Endoscopic Submucosal Dissection (ESD) compared to esophagectomy in treating early esophageal squamous cell carcinoma (EESCC).
This study aimed to evaluate the efficacy and safety of ESD for elderly patients with SEC.
The endoscopic use of cardiac septal occluders has been previously reported as a means to close tracheoesophageal fistulae. In this video, we use a cardiac septal occluder to close a large anastomotic defect that developed in a 69 year old man following esophagectomy and pneumonectomy for squamous cell carcinoma of the left lung and T2N0 adenocarcinoma of the esophagus. The anastomotic defect failed primary surgical repair, and the patient required a chest tube with high output and complicated by repeated chest cavity infections.
Numerous studies on esophageal squamous cell carcinoma (ESCC) have shown that lymph node metastasis occurs in 4.0% to 18.2% of cases with invasion of the muscularis mucosae. According to the Japanese guidelines for diagnosis and treatment of esophageal cancer, tumors invading the muscularis mucosae are relative indications for endoscopic resection (ER). Several studies have shown relatively good outcomes of ER for ESCC invading the muscularis mucosae. However, the median follow-up periods in those studies were less than 5 years.
The magnification endoscopy can observe IPCL on the surface of the esophagus, however the diagnosis accuracy still remains controversial. Three classification methods are used for intrapapillary capillary loops (IPCL) diagnosis currently (Inoue/Arima/JES), which one is better is unclear.
Patients with esophageal squamous cell carcinoma (ESCC) are at a high risk of developing synchronous and metachronous second primary head and neck squamous cell carcinoma (HNSCC). Narrow-band imaging (NBI) is effective in detecting superficial HNSCC. Peroral endoscopic resection of superficial HNSCC is a feasible and effective treatment with curative intent. However, skilled endoscopic technique is necessary to survey the head and neck region to detect the superficial cancer.
The high incidence of synchronous esophageal squamous cell carcinoma (ESCC) (range, 3-14%) in patients with head and neck cancers suggests that endoscopic screening of the esophagus would be appropriate. A combination of narrow-band imaging (NBI) and chromoendoscopy with iodine staining (CEI) has been applied for more than a decade for those patients in Japan. However, it has yet to be proven that additional CEI could offer substantial benefit over NBI alone.