Protective effects of heme oxygenase 1 during ischemia reperfusion injury: Hepatocytes or non-parenchymal cells?

We thank Xu et al. for their insightful comments on our recently published papers in Journal of Hepatology [1] and American Journal of Transplantation [2], in which we documented the importance of macrophage heme oxygenase-1 (HO-1) on macrophage activation and graft autophagy regulation in the pathophysiology of hepatic ischemia-reperfusion injury (IRI).
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research