The burden of uncontrolled A1C in type 1 diabetes: 30  years of insights from the DCCT/EDIC study

In the 1990s, the results of the Diabetes Control and Complication Trial (DCCT) set the standard for the management of type 1 diabetes.1 The trial unequivocally demonstrated that intensive diabetes therapy, based on multiple daily injections of insulin or insulin pump, frequent monitoring of blood glucose, and specific glucose targets, resulted in lower Hemoglobin A1C (A1C) and less microvascular complications than conventional therapy.1 After the trial closeout, patients were encouraged to adopt or to continue the intensive treatment regimen with their own healthcare providers, and their outcomes were followed up in the Epidemiology of Diabetes Interventions and Complications (EDIC) observational study.
Source: Journal of Diabetes and Its Complications - Category: Endocrinology Authors: Source Type: research