Changes in amygdala, cerebellum, and nucleus accumbens volumes in bipolar patients treated with lamotrigine

Bipolar disorder type II (BD-II) is characterized by frequent depressive phases, comorbidities such as anxiety and personality disorders, and high risk for disability and suicidal behaviors (Dell'Osso, Holtzman, Goffin, Portillo, Hooshmand, Miller et  al., 2015; Holma, Haukka, Suominen, Valtonen, Mantere, Melartin et al., 2014; Nordentoft and Mortensen, 2011). BD II patients are also at elevated risk for relapse and recurrence, which increase their risk for self-harm and suicide (Holma et al., 2014).

Source: Psychiatry Research: Neuroimaging - June 12, 2018 Category: Psychiatry Authors: Isabelle E. Bauer, Robert Suchting, Fadwa Cazala, Gokay Alpak, Marsal Sanches, Fabiano G. Nery, Giovana B. Zunta-Soares, Jair C. Soares Source Type: research