Determining the in vitro susceptibility of Neisseria gonorrhoeae isolates from eight cities in Guangdong Province through an improved microdilution method

A microdilution method for the antibiotic susceptibility testing of Neisseria gonorrhoeae was established and improved, and the antibiotic resistance of N. gonorrhoeae samples isolated from eight cities of Guangdong in 2016 was determined. The improved microdilution method was compared with the agar dilution method recommend by the World Health Organization Western Pacific Region by testing the susceptibility of 100 clinical N. gonorrhoeae isolates. The essential agreement (EA), categorical agreement (CA), very major error (VME), major error (ME) and minor error (MIE) levels of the two methods were analyzed, the acceptable performance rates were measured as follows: ≥ 90% for EA or CA, ≤ 3% for VME or ME, and≤7% for MIE.

Source: Diagnostic Microbiology and Infectious Disease - June 12, 2018 Category: Microbiology Authors: Xingzhong Wu, Xiaolin Qin, Jinmei Huang, Feng Wang, Ming Li, Zhizhou Wu, Xiaofeng Liu, Junming Pei, Shanghua Wu, Heyong Chen, Yaohua Xue, Sanmei Tang, Mingheng Fang, Yinyuan Lan, Jiangli Ou, Zhenmou Xie, Yuqi Yu, Jieyi Yang, Wentao Chen, Yunhu Zhao, Hepin Source Type: research