GSE115627 E14.5-born neurons at P3 repress L4 neuron-type and induce L2/3 neuron-type genes upon Kir2.1 in utero electroporation

Contributors : V Ilaria ; T LudovicSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusExperimental in vivo hyperpolarization of E14.5 apical progenitors shifted their transcriptional programs with precocious generation of intermediate progenitors, and a forward shift in the laminar, molecular, morphological and circuit features of their neuronal progeny. In particular, we reported an overall repression of L4-type neuronal genes and a premature induction of L2/3-type neuronal genes following Kir2.1 overexpression.

Source: GEO: Gene Expression Omnibus - June 12, 2018 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research