Pharmacological effect of human melanocortin-2 receptor accessory protein 2 variants on hypothalamic melanocortin receptors

ConclusionsThis is the first dedicated description of single-cell transcriptome signature ofMrap2,Mc3r, andMc4r in the central nerve system and the first evidence describing the unique dimer formation, conformational change, and pharmacological effect of MRAP2 mutations on MC3R signaling.
Source: Endocrine - Category: Endocrinology Source Type: research