Pneumococcal Vaccination (Pneumonia Vaccine)

Title: Pneumococcal Vaccination (Pneumonia Vaccine)Category: Procedures and TestsCreated: 4/12/1999 12:00:00 AMLast Editorial Review: 6/11/2018 12:00:00 AM
Source: MedicineNet Lungs General - Category: Respiratory Medicine Source Type: news

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Publication date: June 2019Source: The Lancet Global Health, Volume 7, Issue 6Author(s): Brian Wahl, Apoorva Sharan, Maria Deloria Knoll, Rajesh Kumar, Li Liu, Yue Chu, David A McAllister, Harish Nair, Harry Campbell, Igor Rudan, Usha Ram, Molly Sauer, Anita Shet, Robert Black, Mathuram Santosham, Katherine L O'Brien, Narendra K AroraSummaryBackgroundIndia accounts for a disproportionate burden of global childhood illnesses. To inform policies and measure progress towards achieving child health targets, we estimated the annual national and state-specific childhood mortality and morbidity attributable to Streptococcus pneum...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Publication date: June 2019Source: The Lancet Global Health, Volume 7, Issue 6Author(s): Li Liu, Yue Chu, Shefali Oza, Dan Hogan, Jamie Perin, Diego G Bassani, Usha Ram, Shaza A Fadel, Arvind Pandey, Neeraj Dhingra, Damodar Sahu, Pradeep Kumar, Richard Cibulskis, Brian Wahl, Anita Shet, Colin Mathers, Joy Lawn, Prabhat Jha, Rakesh Kumar, Robert E BlackSummaryBackgroundIndia had the largest number of under-5 deaths of all countries in 2015, with substantial subnational disparities. We estimated national and subnational all-cause and cause-specific mortality among children younger than 5 years annually in 2000–15 in In...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
CONCLUSIONS: After implementation of a pneumococcal conjugate vaccination program in US children, and despite the herd protection observed in US adults, a persistent burden of PCV13-type CAP remains in this population. PMID: 31072732 [PubMed - as supplied by publisher]
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
Ricardo U. Sorensen1,2,3* 1Professor Emeritus of Pediatrics, Department of Pediatrics, Louisiana State University Health Science Center, New Orleans, LA, United States 2Louisiana Primary Immunodeficiency Network, New Orleans, LA, United States 3Honorary Professor, Faculty of Medicine, University of La Frontera, Temuco, Chile In thisopinion manuscript the author postulates that the present definition of Specific Antibody Deficiency (SAD) needs to be revised and expanded. It is presently defined as a syndrome of low IgG antibody responses to purified Streptococcus pneumoniae capsular polysaccharides vaccine...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Feixia Zheng1*, Xiuyun Ye1, Xulai Shi1, Zhongdong Lin1, Zuqin Yang1 and Longxiang Jiang2* 1Department of Pediatrics, The Second Affiliated Hospital &Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China 2Department of Respiratory Medicine, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Wenzhou, China Background: Hyponatremia has frequently been described as a common complication associated with bacterial meningitis, though its frequency and clinical course in children with bacterial meningitis are unclear. The present study aimed to investigate the frequen...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Discussion This case demonstrates successful cure of pre-B-ALL complicating XLA by alloSCT with restoration of B-cell development and functional antibody response. We are aware of only one previous case of pre-B-ALL in an XLA patient (21), which suggests that human BTK deficiency in itself does not predispose to pre-B-ALL. However, there are data to suggest that BTK may act as a tumor suppressor, and BTK deficiency may predispose to tumor development following a “second hit.” Mice with a genetic deficiency in Slp65, a gene encoding an adaptor protein that functions together with BTK, have a block in progenito...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
CONCLUSION: This is the first cohort study to assess GBS colonization in Western Australian pregnant women and will be highly beneficial for guiding clinical practice and future therapeutic options, in particular, the selection of suitable vaccine candidates. PMID: 31013212 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research
Conclusions: Human challenge studies and systems biology approaches are important tools that should be used in concert to advance our understanding of influenza infection and provide targets for novel therapeutics and immunizations. Introduction Although influenza virus was recognized as an important pathogen over a century ago, influenza continues to cause a significant burden of disease. In the United States alone, it's estimated that in the 2017–2018 season there were 959,000 hospitalizations related to influenza illness, and 79,400 deaths (CDC, 2018). Worldwide, WHO estimates that annual influenza...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
April 13, 2019 - Pfizer Inc. (NYSE: PFE) announced today the presentation of data from a Phase 2 study of its 20-valent pneumococcal conjugate vaccine (20vPnC) candidate, PF-06482077, being investigated for the prevention of invasive disease and...
Source: Drugs.com - Clinical Trials - Category: Pharmaceuticals Source Type: clinical trials
In this study, a “species” is defined as a unique AMR profile, including the profile corresponding to susceptibility to all tested antimicrobials. The AMR profile (or antibiogram) of an isolate is the combination of AMR phenotype (susceptible or non-susceptible) to each drug tested. SR reflects the richness of AMR profiles without weighting of abundance. SE and SD are measures in which both SR and relative abundance are taken into account. The BP diversity index is related to the proportion of isolates with the most common AMR profile. Changes in antimicrobial testing protocol could impact upon results, partic...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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