A cannabinoid receptor 2 agonist reduces blood-brain barrier damage via induction of MKP-1 after intracerebral hemorrhage in rats.

CONCLUSIONS: CB2R agonist alleviated neuroinflammation and protected blood-brain barrier permeability in a rat ICH model. Further molecular mechanisms revealed which is probably mediated by enhancing the expression of MKP-1, then inhibited MAPKs signal transduction. PMID: 29886251 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29886251?dopt=Abstract

Source: Brain Research - June 7, 2018 Category: Neurology Authors: Li L, Yun D, Zhang Y, Tao Y, Tan Q, Qiao F, Luo B, Liu Y, Fan R, Xian J, Yu A Tags: Brain Res Source Type: research

More News: Brain | Brain Cancers | Hemorrhagic Stroke | Neurology | Study