Treatment of Hypertension in Chronic Kidney Disease

AbstractPurpose of ReviewChronic kidney disease (CKD) is recognized as a worldwide epidemic. Hypertension commonly coexists with CKD and its prevalence is progressively increasing as kidney function declines.Recent FindingsFor patients with established CKD and/or diabetes with albuminuria, the updated hypertension guidelines have recommended a blood pressure (BP) goal
Source: Current Hypertension Reports - Category: Primary Care Source Type: research

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Publication date: December 2018Source: Value in Health Regional Issues, Volume 17Author(s): Ramiro E. Gilardino, Eduardo González-Pier, Claudia BrabataAbstractEnd-stage renal disease, the last and most severe stage of chronic kidney disease, represents a major and rising concern for countries in Latin America, driven in large part by aging populations and the near-epidemic rises in diabetes, obesity, and hypertension. This places a great clinical, economic, and social burden on the region’s health systems. During the ISPOR 6th Latin America Conference held in Sao Paulo, Brazil, in September 2017, an educationa...
Source: Value in Health Regional Issues - Category: International Medicine & Public Health Source Type: research
We’re excited to share the topic and questions for this week’s #HITsm chat happening Friday, 8/24 at Noon ET (9 AM PT). This week’s chat will be hosted by Colton Ortolf (@ColtonOrtolf) who blogs at tech prescribed on the topic of “The Role of Technology in Chronic Disease Management“. Chronic disease is an incredibly broad term, but it can be simply defined as “a physical or mental health condition that lasts more than one year and causes functional restrictions or requires ongoing monitoring or treatment.” In all, 86% of $2 trillion in US healthcare expenditures eac...
Source: EMR and HIPAA - Category: Information Technology Authors: Tags: #HITsm Digital Health Healthcare HealthCare IT #HITsm Topics Chronic Care Management Chronic Disease Management Colton Ortolf tech prescribed Source Type: blogs
Publication date: Available online 5 June 2018Source: Seminars in Cell &Developmental BiologyAuthor(s): Robert L. ChevalierAbstractThere is a global epidemic of chronic kidney disease (CKD) characterized by a progressive loss of nephrons, ascribed in large part to a rising incidence of hypertension, metabolic syndrome, and type 2 diabetes mellitus. There is a ten-fold variation in nephron number at birth in the general population, and a 50% overall decrease in nephron number in the last decades of life. The vicious cycle of nephron loss stimulating hypertrophy by remaining nephrons and resulting in glomerulosclerosis h...
Source: Seminars in Cell and Developmental Biology - Category: Cytology Source Type: research
Publication date: Available online 5 June 2018 Source:Seminars in Cell & Developmental Biology Author(s): Robert L. Chevalier There is a global epidemic of chronic kidney disease (CKD) characterized by a progressive loss of nephrons, ascribed in large part to a rising incidence of hypertension, metabolic syndrome, and type 2 diabetes mellitus. There is a ten-fold variation in nephron number at birth in the general population, and a 50% overall decrease in nephron number in the last decades of life. The vicious cycle of nephron loss stimulating hypertrophy by remaining nephrons and resulting in glomerulosclerosis has b...
Source: Seminars in Cell and Developmental Biology - Category: Cytology Source Type: research
ConclusionsBased on the molecular pathway analysis in CKDu patients and review of literature, viral infections and fluoride toxicity appear to be contributing to the molecular mechanisms underlying CKDu.
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research
The epidemic of obesity parallels that of chronic kidney disease (CKD). Obesity worsens the course of CKD mainly defined by an abnormal glomerular filtration rate (GFR). Patients with severe obesity stages (II and III with body mass index, BMI>35 kg/m2) are eligible for bariatric surgery (BS), which is the most efficient method of achieving durable weight loss. BS may reverse glomerular hyperfiltration, albuminuria, improve adipocytokine profile, and relieve diabetes and hypertension. Obesity remission following BS might prevent the progression of renal failure in populations with morbid obesity.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
The epidemic of obesity parallels that of chronic kidney disease (CKD). Obesity worsens the course of CKD, mainly defined by an abnormal glomerular filtration rate (GFR). Patients with severe obesity stages (II and III with body mass index>35 kg/m2) are eligible for bariatric surgery (BS), which is the most efficient method of achieving durable weight loss. BS may reverse glomerular hyperfiltration and albuminuria, improve adipocytokine profile, and relieve diabetes and hypertension. Obesity remission after BS might prevent the progression of renal failure in populations with morbid obesity.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Controversies in Bariatric Surgery Source Type: research
Publication date: December 2018 Source:Value in Health Regional Issues, Volume 17 Author(s): Ramiro E. Gilardino, Eduardo González-Pier, Claudia Brabata End-stage renal disease, the last and most severe stage of chronic kidney disease, represents a major and rising concern for countries in Latin America, driven in large part by aging populations and the near-epidemic rises in diabetes, obesity, and hypertension. This places a great clinical, economic, and social burden on the region’s health systems. During the ISPOR 6th Latin America Conference held in Sao Paulo, Brazil, in September 2017, an educational for...
Source: Value in Health Regional Issues - Category: International Medicine & Public Health Source Type: research
Purpose of review Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN) was identified as the major renal manifestation of HIV infection early in the HIV epidemic. However, HIV infection now is associated with a different spectrum of renal lesions leading to chronic kidney disease. This review examines the changes in kidney injury occurring in the current HIV era and the factors involved in this transformation of disease expression. Recent findings The incidence of HIVAN and opportunistic infections in HIV-infected individuals has declined in concert with the use of effective combination antiretroviral age...
Source: Current Opinion in Nephrology and Hypertension - Category: Urology & Nephrology Tags: RENAL IMMUNOLOGY AND PATHOLOGY: Edited by Agnes B. Fogo Source Type: research
CONCLUSION: Hypertension is strongly related with cardiovascular diseases in CKD patients. Since this relation exists and hypertension leads to cardiovascular diseases, the management of hypertension and increased heart rate should be the main therapeutical target in these patients. PMID: 28875847 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
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