BMP9 regulates cross-talk between breast cancer cells and bone marrow-derived mesenchymal stem cells

Conclusions From our data we conclude that BMP9 inhibits the migration and invasion of breast cancer cells, and promotes the osteoblastic differentiation and proliferation of bone marrow-derived mesenchymal stem cells by regulating cross-talk between these two types of cells through the RANK/RANKL signaling axis.

http://link.springer.com/10.1007/s13402-014-0197-1

Source: Cellular Oncology - September 11, 2014 Category: Cancer & Oncology Source Type: research