White matter abnormalities of the tapetum and their associations with duration of untreated psychosis and symptom severity in first-episode psychosis

In patients with schizophrenia, white matter (WM) abnormalities have been demonstrated across widespread brain regions, including the corpus callosum (Samartzis et al., 2014). The tapetum is a part of the splenium of the corpus callosum that provides anatomical trajectories connecting temporal lobes (Abe et al., 2004). Although the role of the tapetum in schizophrenia remains unknown, some neuroimaging studies showed alterations of WM integrity in the tapetum in patients with schizophrenia (Ellison-Wright et al., 2014) and bipolar psychosis (Lu et al., 2011).
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research