The effect of different treatment strategies on left ventricular myocardial deformation parameters in patients with chronic renal failure

AbstractThe aim of this study was to compare left ventricular (LV) functions by speckle tracking echocardiography (STE) in chronic kidney disease (CKD) patients in various stages and under different renal replacement treatments in order to evaluate possible differences between them. This prospective study included 150 patients with CKD. Renal transplantation patients with glomerular filtration rate greater than 60  ml/min/1.73 m2, patients receiving hemodialysis three times a week, and patients in the predialysis stage with glomerular filtration rate less than 30  ml/dk/1.73 m2 were assigned into Group 1 (n  = 50), Group 2 (n = 50), and Group 3 (n = 50), respectively. LV longitudinal, circumferential, and radial myocardial deformation parameters (strain, strain rate [SR], rotation, twist) were evaluated by STE. Peak systolic longitudinal strain was higher in the transplantation group than t he hemodialysis group (− 19.93 ± 3.50 vs − 17.47 ± 3.28%, p <  0.017). Peak systolic circumferential strain was lower in the hemodialysis group (− 20.97 ± 4.90%) than Groups 1 and 3 (− 25.87 ± 4.20 and − 24.74 ± 4.55%, respectively, p <  0.001). Peak systolic radial SR was higher in the transplantation group than the hemodialysis group (1.84 ± 0.52 vs 1.55 ± 0.52 s−1, respectively, p  <  0.017). Other longitudinal and circumferential deformation parameters together with peak early diastolic rad...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research