Absorbance and light scattering of lenses organ cultured with glucose.

CONCLUSIONS: The absorbance and light scattering of glucose treated lenses in organ culture were quantitated for the first time which could be important for future studies designed to test the efficacy of agents to ameliorate the opacity. Almost all of the glucose related attenuation of light through the human lens was due to light scattering from structural changes and not absorbance from metabolic changes. Glucose caused a more significant effect on the opacity of human lenses compared with rat lenses. The lens model employed could be used to study the efficacy of agents that potentially ameliorate lens opacity. PMID: 29874948 [PubMed - as supplied by publisher]
Source: Current Eye Research - Category: Opthalmology Authors: Tags: Curr Eye Res Source Type: research