No Safety Concerns With Kids' DTaP Combo Vaccine
The shot protects against three potentially serious infectious diseases of childhood, including whooping cough (pertussis). In recent years, the "anti-vaxxer" movement -- a small minority of parents -- has raised concerns that routine childhood immunizations might carry long-term health risks for kids.
Only one-third of pregnant women get flu and Tdap shots, despite the fact they vaccines lower the risks that they and their babies will be hospitalized for the infections, worrying CDC data revel.
(CNN) — Most pregnant women in the United States don’t get flu and whooping cough vaccines even though the shots are safe and recommended as part of routine prenatal care, a report from the US Centers for Disease Control and Prevention said Tuesday. The report said the low rates of vaccination during pregnancy could put moms-to-be and newborns at greater risk of infection, hospitalization and death. The two vaccinations pass on antibodies to the fetus that provide protection after birth, when babies are too young to be vaccinated. It added that pregnant women have more than double the risk of hospitalization if...
In this study we have evaluated whether our OMVs vaccine is capable of overcoming the deficiencies of commercial vaccines in both controlling infections caused by PRN(-) isolate/strain and inducing memory immunity. We found that our OMVs-based formulation has a higher protective capacity against the PRN(-) bacteria than that induced with a commercial aP vaccine. We found that CD4 T cells with a tissue-resident memory (TRM) cell phenotype (CD44+CD62LlowCD69+ and/or CD103+) accumulated in the lungs of mice after the second OMVs vaccine immunization. CD4 TRM cells were also detected in mice immunized with wP vaccine, but not ...
Conclusion: Tdap administration to Korean subjects ≥ 10 years, including pregnant women, for the prevention of diphtheria, tetanus and pertussis was shown to have a well-tolerated safety profile. Trial Registration: ClinicalTrials.gov Identifier: NCT01929291. PMID: 30940999 [PubMed - in process]
Do vaccines cause autism? Is it OK to skip certain vaccines? Get the facts on these and other common questions. Childhood vaccines protect children from a variety of serious or potentially fatal diseases, including diphtheria, measles, mumps, rubella, polio, tetanus, whooping cough (pertussis) and others. If these diseases seem uncommon -- or even unheard of [...]
Conclusions: Pertussis is resurging among infants and young children in Shanghai, and household transmission is the main exposure pathway. The high-virulent strains harboring ptxP3/prn2/ptxC2 and the macrolide-resistant Bordetella pertussis strains are quite prevalent. These issues impose a public health concern in Shanghai. Our findings are important to modify the DTaP vaccination strategy and the management guideline of pertussis in China.
This study shows that adding RTX antigen to an appropriate dose of aP can enhance protection against B. pertussis challenge in mice.
Background: Whooping cough continues being a major cause of morbidity and mortality in infants younger than 1 year old. In 2012 Argentina introduced Tdap in pregnancy to prevent infant mortality. The aim was to describe the clinical and epidemiological profile of Bordetella pertussis comparing pre and post Tdap vaccine periods.
[The Conversation Africa] Over the years vaccines have prevented countless cases of disease and saved millions of lives. Infectious diseases like polio, measles, diphtheria, pertussis (whooping cough), rubella (German measles), smallpox, mumps, tetanus and rotavirus used to be common around the world. Today vaccines can prevent them.
Inviolate Akinyi, a 46-year-old grandmother, got her granddaughter immunized using a mix of private and public clinics. Credit: Veronique Magnin – Habari Kibra VolunteerBy Joyce NgangaNAIROBI, Kenya, Apr 25 2018 (IPS)Inviolate Akinyi, a 46-year-old grandmother, is certain that her grand-daughter needs to get all her vaccines for her to grow up healthy and strong. She uses a mix of private and public clinics in Kibera, one of the largest informal settlement in Nairobi, to get the 15-month-old the shots she needs. Mary Awour, mother to two-year-old Vilance Amondi, also believes immunization is important to protect her ...