Tongue Pressure Measurement and Videofluoroscopic Study of Swallowing in Patients with Parkinson ’s Disease

This study investigated the relationship between tongue pressure during swallowing and dysphagia in patients with Parkinson ’s disease (PD). A total of 24 patients with PD (12 men and 12 women, mean age 70.4 years) were studied. Their mean Hoehn and Yahr scale was 3.0 ± 1.3 (range 1–5). All participants underwent tongue pressure measurement and videofluorography during swallowing. Tongue pressure when swallowin g 5 mL of barium on videofluorography was measured using a sensor sheet with five sensors. Based on the findings of videofluorography, the patients were divided into two groups: dysphagic PD group (n = 9) and non-dysphagic PD group (n = 15). The maximal magnitude (kPa), duration (s), time to peak pressure (s), and pressure gradient (kPa/s) of tongue pressure were analyzed for each part. For duration, time to peak pressure, and pressure gradient, similar values were calculated from the total waveform. There was no significant difference in maximal tongue pressure between the groups. The dysphagic PD group had prolonged duration of tongue pressure and time to peak pressure and a reduced pressure gradient compared with the non-dysphagic PD group. These results indicate that there is a clear difference in the temporal aspe cts of tongue pressure between the non-dysphagic and dysphagic PD patients. These differences provide the characteristics of tongue movement during swallowing in PD patients with dysp...
Source: Dysphagia - Category: Speech-Language Pathology Source Type: research

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Conclusions: This study showed that retinal axonal and neuronal loss is present among collision sport athletes, with most notable differences seen in boxers. These findings are accompanied by reductions in visual function and QOL, similar to patterns observed in multiple sclerosis, Alzheimer and Parkinson diseases. Vision-based changes associated with head trauma exposure that have the potential to be detected in vivo represent a unique opportunity for further study to determine if these changes in collision sport athletes are predictive of future neurodegeneration.
Source: Journal of Neuro-Ophthalmology - Category: Opthalmology Tags: Original Contribution Source Type: research
(MedPage Today) -- Experts call for a shift toward markers within PD itself
Source: MedPage Today Neurology - Category: Neurology Source Type: news
Conditions:   Parkinson Disease;   Virtual Reality Therapy;   Functional Magnetic Resonance Imaging Interventions:   Behavioral: Virtual Reality;   Behavioral: Exercise Therapy;   Drug: Pharmacological Treatment Sponsor:   Farzin Hajebrahimi, PT, MSc Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Luis I. G ómez-Jordana, James Stafford, C. (Lieke) E. Peper, Cathy M. Craig
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Researchers from Seoul National University found that retinas thin as the cells that produce the chemical dopamine die. Dopamine is responsible for coordinating movement.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
European Journal of Neuroscience,Volume 0, Issue ja, -Not available-.
Source: European Journal of Neuroscience - Category: Neuroscience Authors: Source Type: research
AbstractEffective doctor patient relationships are predicated on doctors' relational engagement and affective/holistic communication with the patients. On the contrary, the contemporary healthcare and patient-clinician communication are at odds with the desirable professional goals, often resulting in dehumanization and demoralization of patients. Besides denigrating the moral agency of a patient such apathetic interactions and unprofessional approach also affect the treatment and well-being of the sufferer. Foregrounding multifaceted doctor-patient relationships, graphic pathographies are a significant cultural resource w...
Source: Journal of Medical Humanities - Category: Medical Ethics Source Type: research
AbstractOpen and short circuits of electrode contacts are important technical dysfunctions of DBS. Here, we report on another type of dysfunction restricted to a single electrode contact: impedance instability within regular absolute values. After 9-year subthalamic DBS, a Parkinson patient developed unilateral motor symptoms and intermittent dysaesthesia due to impedance instability of the active contact. DBS efficacy could be restored without surgical revision by activation of the neighboring contact. During 3-year-follow-up, impedances of the dysfunctional contact varied between 1 and 3  kΩ whereas the other ...
Source: Acta Neurochirurgica - Category: Neurosurgery Source Type: research
ConclusionTaken together, our data suggest that β5i is activated in DA neurons under 6-OHDA treatment and may play a neuroprotective role in PD.
Source: Translational Neurodegeneration - Category: Neurology Source Type: research
In conclusion, I really enjoyed the opportunity to use the RightEye system. Working with Dr. Kungle and the RightEye system resulted in the most comprehensive, informative session I’ve ever had about my own vision and left me with clear areas t...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Neurology Neurosurgery Ophthalmology Source Type: blogs
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