Adherence to thyroid hormone replacement therapy: a retrospective, claims database analysis.

CONCLUSIONS: This large, retrospective real-world study demonstrated that adherence to levothyroxine remains a concern among patients with hypothyroidism and that differences in adherence may exist across levothyroxine formulations. PMID: 29874941 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research

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NIH investigators have discovered a series of low molecular weight thyroid-stimulating hormone (TSH) receptor modulators for use in the procedure to detect residual thyroid cancer cells following thyroidectomy. As small molecules, these compounds are orally available and are expected to be less costly and more straightforward to produce than recombinant protein counterparts currently on the market. These compounds appear be orally available, would be less difficult and expensive to produce, and are also more potent and/or specific for the TSH receptor than other known small-molecule TSH receptor agonists. In addition to us...
Source: NIDDK Research Resources - Category: Endocrinology Source Type: research
CONCLUSIONS: Selective SPECT/CT-guided ENI results in significant dose reductions to various organs-at-risk and corresponding NTCP values, and will subsequently reduce the incidence and severity of different troublesome radiation-related toxicities and improve quality-of-life. PMID: 30087057 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
ConclusionAMH levels were decreased in both natural and premature postmenopausal women and could be used as predictor of menopause among women with autoimmune thyroiditis.
Source: Middle East Fertility Society Journal - Category: Reproduction Medicine Source Type: research
Publication date: March 2018Source: Journal of the Egyptian National Cancer Institute, Volume 30, Issue 1Author(s): Mohamed El-Shebiney, Nehal El-mashad, Wael El-mashad, Ahmed A. El-Ebiary, Abdallah E. KotkatAbstractPurposeThe purpose of this study is to determine radiotherapy (RT) dose-volumetric threshold of radiation-induced hypothyroidism (HT) in head and neck squamous cell carcinoma (HNSCC) patients.Patients and methodsThe diagnosis of HT in 78 HNSCC patients treated with RT was based on a thyroid stimulating hormone (TSH) level greater than the maximum value of laboratory range. In all patients, dose-volumetric param...
Source: Journal of the Egyptian National Cancer Institute - Category: Cancer & Oncology Source Type: research
ConclusionAMH levels were decreased in both natural and premature postmenopausal women and could be used as predictor of menopause among women with autoimmune thyroiditis.
Source: Middle East Fertility Society Journal - Category: Reproduction Medicine Source Type: research
Publication date: March 2018Source: Journal of the Egyptian National Cancer Institute, Volume 30, Issue 1Author(s): Mohamed El-Shebiney, Nehal El-mashad, Wael El-mashad, Ahmed A. El-Ebiary, Abdallah E. KotkatAbstractPurposeThe purpose of this study is to determine radiotherapy (RT) dose-volumetric threshold of radiation-induced hypothyroidism (HT) in head and neck squamous cell carcinoma (HNSCC) patients.Patients and methodsThe diagnosis of HT in 78 HNSCC patients treated with RT was based on a thyroid stimulating hormone (TSH) level greater than the maximum value of laboratory range. In all patients, dose-volumetric param...
Source: Journal of the Egyptian National Cancer Institute - Category: Cancer & Oncology Source Type: research
Authors: Pomahacova R, Zamboryova J, Paterova P, Fiklik K, Cerna Z, Lad V, Skalicka E, Huml M, Sykora J Abstract BACKGROUND: The prevalence of autoimmune thyroiditis (AIT), as the most common autoimmune disease (AD) and papillary thyroid cancer (PTC) is steadily rising in children. The aim of this study was to determine the coexistence of other AD and thyroid carcinoma (TC) in AIT. METHODS: The cross-sectional study conducted at a tertiary center comprised AIT children (
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - Category: Biomedical Science Tags: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Source Type: research
CONCLUSION: Higher all-cause mortality among those with excess iodine intake, compared with individuals with adequate iodine intake, highlights the importance of monitoring population iodine status. Further studies with longitudinal measures of iodine status are needed to validate our results and assess the potential risks excess iodine intake may have on long-term health outcomes. PMID: 29882490 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
Conclusion: Screening breast cancer patients for thyroid function status at baseline and serially post-treatment to evaluate the need for thyroid hormone replacement may provide for a novel strategy for treating chemotherapy-induced fatigue. PMID: 29876020 [PubMed]
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Authors: Valea A, Georgescu CE Abstract Selenium (Se) has a multilevel, complex and dynamic effect on the human body as a major component of selenocysteine, incorporated into selenoproteins, which include the selenocysteine-containing enzymes iodothyronine deiodinases. At the thyroid level, these proteins play an essential role in antioxidant protection and hormone metabolism. This is a narrative review based on PubMed/Medline database research regarding thyroid physiology and conditions with Se and Se-protein interferences. In humans, Se-dependent enzyme functions are best expressed through optimal Se intake, alth...
Source: Hormones - Category: Endocrinology Tags: Hormones (Athens) Source Type: research
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