Mass. Researchers May Be On Brink Of Creating Revolutionary, Non-Addictive Painkiller

CAMBRIDGE (CBS NEWS) — Researchers in Massachusetts believe they may be on the brink of creating a revolutionary non-addictive painkiller. Developed by Blue Therapeutics, Blue-181 could be a big step forward in dealing with the growing opioid crisis. The team there said it wanted to make a drug that is a total replacement for the opioids currently on the market – something that people could safely stop using without the possible dangerous side effects. Mark Loccisano felt a gratification from painkillers with his very first pill. They were prescribed by a doctor for a sports injury. It was the beginning of an opioid addiction that consumed his 20s and nearly cost him his life, reports CBS News’ Kenneth Craig. “Not many people know they’re addicts until they start using,” Loccisano said. “I ended up wrapping my work truck around a telephone pole one night, on my way home from work….And that wasn’t even enough for me to stay clean.” Loccisano is now in treatment at St. Christopher’s Inn, which is run by a ministry of the Franciscan Friars of the Atonement in Garrison, New York. He’s part of a staggering number of Americans swept up in the nation’s opioid epidemic. But now, three Harvard-trained scientists believe they’ve developed a breakthrough: a non-narcotic, non-addictive painkiller 50 times more powerful than morphine. “We were told the same thing about the painkillers currently on t...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Cambridge Local TV opioid crisis Source Type: news

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CONCLUSION: VR was helpful in reducing BoNT procedure-related discomfort in a majority of patients. Challenges with VR setup, patient tolerance, and selecting viewing experiences were identified to guide further research and use of VR in a clinical environment. PMID: 30223406 [PubMed - as supplied by publisher]
Source: Journal of Pediatric Rehabilitation Medicine - Category: Rehabilitation Tags: J Pediatr Rehabil Med Source Type: research
Authors: Fisher MT, Zigler CK, Houtrow AJ Abstract PURPOSE: To evaluate variables that modulate pain during intramuscular botulinum toxin A injections in children. METHODS: As part of a Quality Improvement project, this retrospective analysis compared reported pain during and five minutes post injections with patient and procedural variables using subgroup and regression analyses (N= 593 procedures with 249 unique patients). RESULTS: Mean procedural pain for all procedures (n= 563) was 3.8 ± 3.0. Most children reported no pain (83.8%) or mild pain (12.1%) five minutes after the procedure. Provider, p...
Source: Journal of Pediatric Rehabilitation Medicine - Category: Rehabilitation Tags: J Pediatr Rehabil Med Source Type: research
Conclusion Based on our findings it seems that MSU classification can be used in patients' selection to achieve the best treatment outcome after intradiscal ozone injection among patients with lumbar disc herniation. PMID: 30227808 [PubMed - as supplied by publisher]
Source: Interventional Neuroradiology - Category: Radiology Tags: Interv Neuroradiol Source Type: research
Clark County is about to get its first freestanding emergency department in October 2019, thanks to Mercy Health — Springfield. The $14 million freestanding emergency department, expected to break ground in October of this year, will feature 10 exam rooms with the capacity to hold patients overnight, as well as a landing pad for medical helicopters to transfer out more critical patients. Services inside th e facility will include a chest pain center; lab and imaging center with CT (computerized…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Motor output maps within primary motor cortex are widely distributed and modified by motor skill learning and neurological injury. Functions that these maps represent after spinal cord injury remain debatable. Moreover, the pattern of reorganization and wh...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Overprescription of postoperative opioid medication is a contributor to the opioid abuse epidemic in the United States, and regulatory bodies suggest that patients be limited to 7 days or
Source: Journal of Vascular Surgery - Category: Surgery Authors: Tags: Abstract from the 2018 New England Society for Vascular Surgery Annual Meeting Source Type: research
It was devastating at the time, but I met amazing people who helped me pursue a career in medical scienceI was 14 years old when I was told I had cancer. It was just before Christmas in 2009 and I ’d had terrible pain in my side for several weeks. After being seen at four different hospitals, I ended up at Birmingham children’s hospital. It was there that I was told I had alveolar rhabdomyosarcoma, words that meant absolutely nothing to me at first. I soon realised they meant cancer.Before my diagnosis, I was far more concerned with schoolwork and my friends – normal things 14-year-olds have to deal with....
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Society Health Cancer Cancer research Medical research Science Careers Education Students Higher education Children NHS Source Type: news
A Marine veteran shares the struggles of dating while on medication for his service-related PTSD and chronic pain.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Dating and Relationships Viagra (Drug) Veterans Tinder (Mobile App) Source Type: news
Authors: Aydın A, Atiç R Abstract OBJECTIVE: The aim of the study was to evaluate and compare clinical and demographic characteristics, functional status and quality of life among patients who underwent amputation for the most common reason in our region. METHODS: Demographic data, level of and reasons for undergoing amputation and clinical data on the use of prostheses in 126 patients were recorded. The amputees were divided into three groups: vascular, trauma and landmine. Variables related to clinical and demographic characteristics, daily life activities and quality of life were investigated. Durati...
Source: Journal of Back and Musculoskeletal Rehabilitation - Category: Orthopaedics Tags: J Back Musculoskelet Rehabil Source Type: research
Authors: Çatalbaş N, Akkaya N, Atalay NS, Sahin F Abstract BACKGROUND: Clinical and electrophysiological effects of therapeutic ultrasound (US) were researched in many studies on patients with CTS with conflicting results. OBJECTIVE: To assess the effects of continuous and pulsed US treatments by ultrasonographic imaging in addition to clinical and electrophysilogical parameters in patients with carpal tunnel syndrome (CTS). METHOD: Fifty-four patients with idiopathic CTS were randomly divided into three groups. All patients used night splints for two weeks. In addition to splint therapy, continuous...
Source: Journal of Back and Musculoskeletal Rehabilitation - Category: Orthopaedics Tags: J Back Musculoskelet Rehabil Source Type: research
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