Mass. Researchers May Be On Brink Of Creating Revolutionary, Non-Addictive Painkiller

CAMBRIDGE (CBS NEWS) — Researchers in Massachusetts believe they may be on the brink of creating a revolutionary non-addictive painkiller. Developed by Blue Therapeutics, Blue-181 could be a big step forward in dealing with the growing opioid crisis. The team there said it wanted to make a drug that is a total replacement for the opioids currently on the market – something that people could safely stop using without the possible dangerous side effects. Mark Loccisano felt a gratification from painkillers with his very first pill. They were prescribed by a doctor for a sports injury. It was the beginning of an opioid addiction that consumed his 20s and nearly cost him his life, reports CBS News’ Kenneth Craig. “Not many people know they’re addicts until they start using,” Loccisano said. “I ended up wrapping my work truck around a telephone pole one night, on my way home from work….And that wasn’t even enough for me to stay clean.” Loccisano is now in treatment at St. Christopher’s Inn, which is run by a ministry of the Franciscan Friars of the Atonement in Garrison, New York. He’s part of a staggering number of Americans swept up in the nation’s opioid epidemic. But now, three Harvard-trained scientists believe they’ve developed a breakthrough: a non-narcotic, non-addictive painkiller 50 times more powerful than morphine. “We were told the same thing about the painkillers currently on t...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Cambridge Local TV opioid crisis Source Type: news

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The obese 48-year-old, from New York, would drink up to eight sugary sodas a day, which made up a staggering 42 per cent of his daily calorie intake. He was prescribed acetazolamide.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
The FDA is set to crack down on sales of flavored e-cigarette products, claiming they are highly addictive and have become hugely popular with minors. It could take action as soon as next week. Anna Werner reports.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
Premier Health is one of the largest companies in the Dayton region, and it's also heavily involved in the community. "Supporting the community — specifically taking steps to advance the health of local residents — is core to our health system’s mission," said Mary Boosalis, president and CEO of Premier Health. Some of the most recent examples of Premier's support of community-based initiatives include G em City Market, Wesley Community Center and the Community Overdose Action Team. It also…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Authors: Majanović SK, Zelić M, Belančić A, Licul V, Vujičić B, Girotto N, Štimac D Abstract Diabetic gastroparesis (DGP), a delay in gastric emptying without obstruction to outflow as a complication of diabetes, typically develops after at least 10 years of diabetes. Cardinal symptoms include nausea, vomiting, early satiety, bloating, and upper abdominal pain. The aim of DGP treatment is to alleviate the severity and frequency of symptoms, improve the level of gastric emptying, ameliorate the patient's nutritional status and to optimize glycemic control. In the treatment of chronic drug-refractory nau...
Source: Peritoneal Dialysis International - Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research
Erwin Idoux, Michele Tagliabue, Mathieu Beraneck
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusiones: Por su elevada prevalencia, el SDTM constituye un foco interesante de acción a la hora de optimizar los tratamientos y minimizar el gasto dentro de las entidades maxilofac iales. Este trabajo pone de manifiesto la situación actual y alerta sobre la necesidad de elaborar protocolos de derivación en consenso con Atención Primaria.ABSTRACT Introduction: Temporomandibular joint syndrome (TMJS) includes a wide range of signs and symptoms that vary from mild pain in masticatory muscles to inability to open and close the mouth, and even irreversible joint derangement. Management is contro...
Source: Revista Espanola de Cirugia Oral y Maxilofacial - Category: ENT & OMF Source Type: research
How was the unusual origin of this patient's left-sided flank pain determined?Applied Radiology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Radiology Journal Article Source Type: news
ConclusionAASK is simple to assess using existing validated questionnaires. AASK performs well in individuals with and without OA and should be considered in clinical trials and observational studies of early knee OA.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
ConclusionOPCCs for HF primarily focused on evaluating symptoms (i.e., mood, dyspnea), advance directive/code status, caregiver/family support, functional status, and on recommending care coordination and referrals. There were considerable regional differences in OPCC assessment and recommendation practices. Results may be biased by disparate OPCC documentation templates at each site.  Additional measures, such as uniform charting templates, are needed to ensure that OPCCs for HF patients are comprehensive and standardized.ResultOf 61 ENABLE CHF-PC participants, 39 (64%) had an OPCC (Northeast site, n=27; Southea...
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
ConclusionsThe educational intervention was designed to increase awareness and understanding of the nursing staff regarding the nature, characteristics, negative outcomes, and costs of delirium, as well as the success and net monetary benefit of prevention protocols. The educational program focused on practical strategies derived from the NICE Clinical Guideline 103. Delirium prevention reduces length of stay, healthcare costs, and nursing hours per patient day. Prevention also improves patient outcomes. The minimal costs of the protocol will increase nursing and administrative support for prevention interventions.Nurses a...
Source: Heart and Lung: The Journal of Acute and Critical Care - Category: Respiratory Medicine Source Type: research
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