Professor (W1 with tenure track to W2) for Molecular Medicine of Life-threatening Infections

Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news

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Publication date: Available online 19 January 2019Source: Journal of BiotechnologyAuthor(s): Mateusz Wojtusik, Priscilla Vergara, Juan C. Villar, Felix Garcia-Ochoa, Miguel LaderoAbstractThe stabilization effects on a novel commercial β-glucosidase preparation from Aspergillus fumigatus during saccharification of ethanol-water pretreated wheat straw were analysed in comparison to this enzyme stability during cellobiose hydrolysis. For this purpose, the kinetics of β-glucosidase residual activity during cellobiose hydrolysis from 40 till 70 °C were studied, resulting in the fitting of a first-order part...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
Publication date: Available online 18 January 2019Source: Journal of BiotechnologyAuthor(s): Li-Nian Cai, Sheng-Nan Xu, Tao Lu, Dong-Qiang Lin, Shan-Jing YaoAbstractThe hydrolysis step by β-glucosidase (BGL) is generally recognized as the major limiting step in cellulose degradation and the BGLs with prominent enzymatic properties are of great importance for efficient utilization of lignocellulosic biomass. In order to identify some salt-tolerant BGLs, two BGL genes were cloned from marine Aspergillus niger ZJUBE-1 genome. Then two bgl expression cassettes driven by gpdA promoter were respectively transformed into mar...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
In this study, seven chitinases from different bacteria and fungi were produced, characterized and their biocontrol abilities against graminaceous stem borers Eldana saccharina, Chilo partellus and Sesamia calamistis were assessed. All chitinases were stable over broad ranges of pH and temperature, however, recombinant fungal chitinases were more acid-stable than the bacterial counterparts. Chitinases from the thermophilic filamentous fungi Thermomyces lanuginosus SSBP (Chit1) and from Bacillus licheniformis (Chit lic) caused 70% and 80% mortality, respectively, in second instar larvae of E. saccharina. Six of the sev...
Source: Journal of Bioscience and Bioengineering - Category: Biomedical Science Source Type: research
In this study, a natural antimicrobial cationic peptide of epsilon-poly-l-lysine (EPL) decorated ordered mesoporous silica (SBA-15) was facilely prepared for the efficient loading of antifungal itraconazole (ITZ) drugs. The characterized mesoporous SBA-15/EPL/ITZ composite exhibited remarkable antifungal performance against Aspergillus fumigatus as a model mold, which was attributed to synergistic antifungal activities of ITZ and EPL in the mesopores. Moreover, the in vitro release behaviors of ITZ in the composite nanoexcipients both in simulated gastric fluid and fasted state simulated intestinal fluid were studied. The ...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
Conclusion: Our results clearly indicate that ATF4 was involved in the host antifungal immune response to A. fumigatus keratitis; expression was found to be dependent on TLR4, LOX-1 expression, and MAPKs pathway. PMID: 30647960 [PubMed]
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
CONCLUSION: The outcomes of this study exhibit a light towards a new step of heavy metal bioremediation. PMID: 30648900 [PubMed - as supplied by publisher]
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research
Microbial Drug Resistance, Ahead of Print.
Source: Microbial Drug Resistance - Category: Microbiology Authors: Source Type: research
This study demonstrates the great potential of Y. lipolytica as an industrial platform for itaconic acid production. PMID: 30656392 [PubMed - as supplied by publisher]
Source: Applied Microbiology and Biotechnology - Category: Microbiology Authors: Tags: Appl Microbiol Biotechnol Source Type: research
Thu, 01/17/2019 - 13:21News blog
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Thu, 01/17/2019 - 13:13News blog
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
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