Professor (W1 with tenure track to W2) for Molecular Medicine of Life-threatening Infections

Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news

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Publication date: Available online 19 August 2018Source: Journal of BiotechnologyAuthor(s): Chao Li, Wei Shu, Shuai Wang, Peng Liu, Yingpping Zhuang, Siliang Zhang, Jianye XiaAbstractEnvironmental gradient is an important common issue during scale-up process for protein production. To address the dynamic regulatory mechanism of Aspergillus niger being exposed to inhomogeneous glucose concentrations, glucose perturbation were experimented on the steady state of A. niger chemostat culture, and dynamic profiles of the intracellular metabolites in central carbon metabolism were tracked in a time scale of seconds. The upper gly...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
Publication date: Available online 19 August 2018Source: Marine ChemistryAuthor(s): Maria Michela Salvatore, Rosario Nicoletti, Francesco Salvatore, Daniele Naviglio, Anna AndolfiAbstractIn the last decades the increasing awareness by the scientific community of the importance to exploit natural resources for the finding of new bioactive products has stimulated a huge research activity concerning the marine biological resources, and advanced strategies have been developed for investigations on microbial metabolomics. Gas chromatography coupled to mass spectrometry represents a valuable technology in this respect. The prese...
Source: Marine Chemistry - Category: Chemistry Source Type: research
Conclusions: Our preliminary study is useful to further clarify the etiopathology of vulvodynia and suggest new therapeutic strategies for approaching the VVS. PMID: 30116438 [PubMed]
Source: Clin Med Res - Category: Research Authors: Tags: J Clin Med Res Source Type: research
op Daniela Hanganu The biological properties and main phenolic compounds of the O. vulgare L. ssp. vulgare extract are described in the present paper. The polyphenolic compounds were analyzed by chromatographic and spectrophotometric techniques. The antioxidant potential was evaluated using several methods: CUPRAC (cupric ion reducing antioxidant capacity), FRAP (ferric reducing ability of plasma), inhibition of lipid peroxidation catalyzed by cytochrome c, and superoxide (SO) scavenging assays. The antimicrobial activity of the oregano extract was evaluated by means of agar-well diffusion assay. The hepatoprotective...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
ConclusionHowever, a fully and systematically discussion of the methods of detoxification for aflatoxins is still not available. Therefore, in the present review we briefly enumerate several traditional strategies, update newly methods, particularly the potential use of natural phytochemicals, and discuss some mechanisms during the detoxification period, summarizing merits and demerits of these methods. We suggest that this important information and our humble opinions could help researchers to understand the degradation of methods for aflatoxins.Graphical abstract
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research
Publication date: Available online 18 August 2018Source: Current Opinion in Food ScienceAuthor(s): Fábio Rocha-Miranda, Armando VenâncioThe increasing consumption of plant-based products for health promotion or for disease treatment has generated public health concerns, since herbs or plants are in direct contact with soils and may easily be colonized by fungi. Many studies have shown the contamination of plant-based supplements and drugs with mycotoxigenic fungal species. Aspergillus and Penicillium species have been reported as the most frequent and dominant ones, with records of the occurrence of many mycot...
Source: Current Opinion in Food Science - Category: Food Science Source Type: research
The objective of this work was to explore the storage properties of a structured oil-in-water emulsion containing both water- and fat-soluble bioactive compounds from bilberries (Vaccinium myrtillus L.). Bilberry seed oil (BSO) was dispersed in a continuous aqueous phase of anthocyanins (AC) and whey protein isolate. The microstructure was evaluated using light microscopy and the effect of anthocyanins on lipid oxidation and microbial growth was investigated. The results showed that it was possible to generate a stable emulsion structure that resisted phase separation during 25 weeks of storage. Gas chromatography–...
Source: Food Chemistry - Category: Food Science Source Type: research
Publication date: Available online 12 August 2018Source: Carbohydrate PolymersAuthor(s): C. Nobre, D.A. Gonçalves, J.A. Teixeira, L.R. RodriguesAbstractAn integrated process enabling the simultaneous production and purification of fructo-oligosaccharides (FOS) was explored. A co-culture fermentation with Aspergillus ibericus (used as FOS producer strain) and Saccharomyces cerevisiae YIL162 W (for small saccharides removal) was optimized. Inoculation conditions of S. cerevisiae, fermentative broth composition, temperature and pH were optimized by experimental design. Yeast extract concentration and temperature...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Publication date: Available online 16 August 2018Source: Toxicology ReportsAuthor(s): G.K. Omeiza, J. Kabir, J.K.P. Kwaga, C.N. Kwanashie, M. Mwanza, L. NgomaAbstractNigeria, being a tropical nation, characterized by favorable climatic conditions, may display high chances of feed contaminations due to aflatoxigenic Aspergillus flavus with the consequences of health risks associated with the consumption of dairy products. A cross-sectional study was conducted to examine the risks of occurrence and distribution of aflatoxigenic Aspergillus flavus (A. flavus) and aflatoxin B1 (AFB1) contamination levels based on the European ...
Source: Toxicology Reports - Category: Toxicology Source Type: research
n RA, Houbraken J Abstract Aflatoxins and ochratoxins are among the most important mycotoxins of all and producers of both types of mycotoxins are present in Aspergillus section Flavi, albeit never in the same species. Some of the most efficient producers of aflatoxins and ochratoxins have not been described yet. Using a polyphasic approach combining phenotype, physiology, sequence and extrolite data, we describe here eight new species in section Flavi. Phylogenetically, section Flavi is split in eight clades and the section currently contains 33 species. Two species only produce aflatoxin B1 and B2 (A. pseud...
Source: Studies in Mycology - Category: Biology Authors: Tags: Stud Mycol Source Type: research
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