Study: Newly discovered sperm structure may contribute to infertility
A newly discovered sperm structure may play a role in infertility, miscarriages and birth defects, and could lead to new diagnostics and therapeutic methods.
In an interview about her new memoir, "Becoming," the former first lady opened up about miscarriage and infertility
ConclusionPresence of adenomyosis seems to have adverse effects on IVF outcomes in clinical pregnancy rate, live birth rate and miscarriage rate. Screening for adenomyosis might be considered before ART so that the couple has better awareness of the prognosis.
Publication date: Available online 22 October 2018Source: Reproductive BioMedicine OnlineAuthor(s): SpanishInfertility SWOT Group (SISG), MA Checa, J Bellver, E Bosch, JJ Espinós, F Fabregues, J Fontes, J García-Velasco, A RequenaAbstractHysteroscopic septum resection in women with unfavourable reproductive and clinical outcomes has become common practice worldwide to improve reproductive results. No clear evidence on the possible advantages and drawbacks of this procedure has been published. In this opinion paper, based on a SWOT (strengths, weaknesses, opportunities, threats) analysis, the different aspects...
The objective of this study was to demonstrate a markedly enlarged isthmocele, that resulted in the miscarriage of a 12-week IVF twin pregnancy.
Objective: To evaluate whether a novel technique of hysteroscopic metroplasty (PALPATOR-metroplasty) may maximize reproductive outcomes in women with partial or complete uterine septum (US) by achieving an optimal fundal thickness.
This study investigated the quality and quantity of eggs and embryos as well as the clinical pregnancy outcome in young infertile women with diminished ovarian reserve (DOR) after in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). MATERIAL AND METHODS We retrospectively reviewed records of 4285 infertile women and divided them into 3 groups according to age and ovarian reserve: young women with normal ovarian reserve (n=1695), young women with DOR (n=1121), and older women with DOR (n=1469). RESULTS In young women with DOR, the proportion of high-quality embryos was significantly higher than in older women...
ConclusionHysteroscopic surgery using cold graspers combined with electric loop by the HEOS is feasible and effective for treatment of DUL as it preserves the uterus and yields favorable reproductive outcomes. The cold surgery and fenestration method minimize electrical and thermal damage to the endometrium surrounding the myoma, consequently reducing surgical risks.
(Abstracted from Aging Cell 2017;16:1381–1393) The growing oocyte is one of the most translationally active cells in the body and must accumulate high-quality, maternally derived proteins to support subsequent embryo development. Women of advanced reproductive age are at increased risk of infertility, miscarriages, and birth defects because of a marked decline in oocyte quality.
CONCLUSIONS: Given its potential to reduce the miscarriage rate, LT4 supplementation is recommended for infertile women with SCH and/or TAI who are undergoing IVF/ICSI. However, additional population-based RCTs are needed to confirm this recommendation. PMID: 30249251 [PubMed - in process]
ConclusionIn light of connecting etiological link between infertility and RM as reviewed in this study, interrogating the oocyte-specific genes with suspected roles in reproductive biology, in cases of unexplained RM, may open new possibilities in widening our understanding of RM pathophysiology.