Study: Newly discovered sperm structure may contribute to infertility

A newly discovered sperm structure may play a role in infertility, miscarriages and birth defects, and could lead to new diagnostics and therapeutic methods.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news

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Publication date: Available online 19 February 2019Source: Journal of Minimally Invasive GynecologyAuthor(s): Keiji Kuroda, Yuko Ikemoto, Asako Ochiai, Rie Ozaki, Yuko Matsumura, Shuko Nojiri, Koji Nakagawa, Rikikazu SugiyamaABSTRACTStudy ObjectiveTo analyze the clinical outcomes and predictive factors for the therapeutic effect of combination treatment of preoperative embryo cryopreservation and endoscopic surgery (‘surgery-assisted reproductive technology [ART] hybrid therapy’) in infertile women with diminished ovarian reserve (DOR) with uterine fibroids and/or ovarian endometriomas.DesignA retrospective coh...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Introduction: Either appearing after miscarriage or abortion by request, the trophoblastic retention is often easy to diagnose, but the management can be difficult. Therefore, severe consequences may appear: endometritis, infertility, intrauterine adhesions, persistent molar pregnancy.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Oral Poster at Breakfast 7 – EARLY PREGNANCY LOSS and ECTOPIC Source Type: research
Introduction: There is a high frequency of subclinical forms of thyroid pathology, prevalence of infertility, miscarriage, but there is no single one thought about the need for screening programs, tactics of preconceptual training.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Basic Science 3 – Obstetrics and Caring for women in distress Source Type: research
Publication date: Available online 15 February 2019Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Theodoros D. Theodoridis, Panagiotis Pappas, Grigoris F. GrimbizisAbstractThe prevalence of congenital uterine anomalies (CUA) is reported to be 4,3-6,7% in the general population, 3,4-8% in the infertile population and 12,6-18,2% among those with recurrent miscarriages. They are the result of abnormal formation, differentiation and fusion of the Mu¨llerian or paramesonephric ducts during fetal life.Until now, various classification systems have been proposed for the categorization of Co...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
CONCLUSION: In women with infertility undergoing fertility work-up, tubal flushing with oil-based contrast probably increases clinical pregnancy rates within 6 months and may increase subsequent live birth rates, compared to tubal flushing with water-based contrast and compared to no intervention. Evidence on fertility outcomes beyond 6 months is insufficient. This article is protected by copyright. All rights reserved. PMID: 30740799 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
AbstractStudy objectiveTo compare pregnancy outcomes in PCOS women undergoing transvaginal ovarian injury (TVOI) and laparoscopic ovarian drilling (LOD)Design126 infertile patients with PCOS were included in this prospective cohort studyCanadian task force classification of level of evidenceIIA.SettingUniversity-affiliated fertility center.PatientsSixty-seven infertile patients with the history of failed in vitro maturation underwent follow-up as the TVOI group. Fifty-nine infertile women who underwent LOD acted as controls. All subjects had PCOS with menstrual irregularity and were anovulatory by repetitive serum progeste...
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
CONCLUSION: Although limited by heterogeneity, studies of ovarian stimulation in women with unexplained infertility show no difference in clinical outcomes between letrozole and clomiphene citrate. PMID: 30741800 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
The objective of the present systematic review and meta-analysis was to compare surgical and expectant management of endometriomas regarding IVF outcomes. Prospective and retrospective controlled studies were found via the Cochrane Library, Embase, and MEDLINE databases. Thirteen studies (1 randomized controlled trial and 12 observational studies, N = 2878) were pooled, and similar live birth rates were observed in the surgically and expectantly managed groups (odds ratio = 0.83; 95% confidence interval [CI], 0.56–1.22; p = .98). The clinical pregnancy rates (odds ratio = 0.83; 95% CI, 0.66–1.05...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Publication date: 2–8 February 2019Source: The Lancet, Volume 393, Issue 10170Author(s): David Miller, Susan Pavitt, Vinay Sharma, Gordon Forbes, Richard Hooper, Siladitya Bhattacharya, Jackson Kirkman-Brown, Arri Coomarasamy, Sheena Lewis, Rachel Cutting, Daniel Brison, Allan Pacey, Robert West, Kate Brian, Darren Griffin, Yakoub KhalafSummaryBackgroundSperm selection strategies aimed at improving success rates of intracytoplasmic sperm injection (ICSI) include binding to hyaluronic acid (herein termed hyaluronan). Hyaluronan-selected sperm have reduced levels of DNA damage and aneuploidy. Use of hyaluronan-based sp...
Source: The Lancet - Category: General Medicine Source Type: research
ConclusionFour different types of endometrial preparation methods for FET cycles appear to be equally effective in terms of implantation, pregnancy, miscarriage and live birth rates in women with normal menstrual cycles.Clinical Trial Registration Number: NCT02251925.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
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