Family occurrence of autoimmune hepatitis: A Danish nationwide registry-based cohort study

Autoimmune hepatitis (AIH) is a chronic autoimmune liver disease with an incidence of 1 per 100.000 population per year around the world [1]. It is a frequently held notion that AIH accumulates in families [2], but the degree of familial clustering has rarely been studied. The existing literature suggests that AIH accumulates in twins [3,4], siblings [5], parents and children [3,6 –8], second-degree relatives [3], and family members of unspecified relationship [9,10], but those studies were limited by small numbers of patients and did not compare AIH incidence with the general population.

Source: Journal of Hepatology - June 6, 2018 Category: Gastroenterology Authors: Lisbet Gr ønbæk, Hendrik Vilstrup, Lars Pedersen, Kaare Christensen, Peter Jepsen Source Type: research