Anthropometric factors and non-Hodgkin ’s lymphoma risk: Systematic review and meta-analysis of prospective studies

The associations between anthropometric factors and non-Hodgkin ’s lymphoma (NHL) risk remain inconclusive. A meta-analysis was performed to clarify these associations. PubMed and Web of Science were searched for relevant prospective observational studies. A random-effects model was used to generate the summary relative risks (RRs) with 95% confidence interval s (CIs). A total of 22 prospective cohort studies, with over 20,000 NHL cases, were included in the present meta-analysis. The summary RRs of NHL risk were 1.06 (95% CI 1.03, 1.09) for each 5 kg/m2 increase in body mass index (BMI), 1.11 (95% CI 1.07, 1.16) for each 5 kg/m2 increase in BMI in ea rly adulthood (aged 18-21 years), 1.05 (95% CI 1.01, 1.09) for each 10 kg increase in weight, 1.21 (95% CI 1.15, 1.28) for each 10 kg increase in weight in early adulthood (aged 18-21 years), and 1.13 (95% CI 1.10, 1.17) for each 10 cm increase in height.
Source: Critical Reviews in Oncology Hematology - Category: Cancer & Oncology Authors: Source Type: research