Ukrainian clinic has successfully created FOUR 'three-parent babies' for infertile women
An experimental process is being performed at the Nadiya Clinic in Kiev, Ukraine, where the DNA of three people is being used to create babies for couples that have been struggling with infertility.
After an endometriosis diagnosis, Ash launched a program that matches individuals struggling with infertility with mentors who already had been through the process.
ConclusionsThis study demonstrated that CFAP43 and CFAP44 mutations are important causes of MMAF in the Chinese population. These novel mutations broaden the spectrum of CFAP43 and CFAP44 mutations.
Publication date: Available online 16 March 2019Source: Reproductive BioMedicine OnlineAuthor(s): Kai J. Buhling, Annika Schumacher, Christine zu Eulenburg, Elena LaakmannAbstractTo study the evidence of the influence of micronutrient supplementation on male fertility based on published research and to make recommendations for micronutrient supplementation for men suffering from infertility.18 randomised, double-blind, placebo-controlled trials were included in the meta-analysis or in the systematic review.A significant improvement in semen parameters was evident for selenium (200 g orally, daily) and L-carnitine (LC; 2 g ...
Genesis, genes and epigenetics of endometriosis-associated infertility, Published online: 18 March 2019; doi:10.1038/s41574-019-0191-9Jae-Wook Jeong and colleagues report that histone deacetylase 3 (HDAC3) is downregulated in the endometrium of women with endometriosis. In addition, they show that the loss of HDAC3 is associated with aberrant hormonal signalling and increased fibrosis in the endometrium and impaired endometrial receptivity.
AbstractUbiquitin-specific protease 26 (USP26) is a deubiquitylating enzyme belonging to the USPs family with a transcription pattern restricted to the male germline. Since protein ubiquitination is an essential regulatory mechanism during meiosis, many efforts have been focused on elucidating the function of USP26 and its relationship with fertility. During the last decade, several studies have reported the presence of different polymorphisms inUSP26 in patients with non-obstructive azoospermia (NOA) or severe oligozoospermia suggesting that this gene may be associated with human infertility. However, other studies have r...
Authors: Gill K, Jakubik J, Kups M, Rosiak-Gill A, Kurzawa R, Kurpisz M, Fraczek M, Piasecka M Abstract INTRODUCTION: Contemporary professional jobs that often enforce a sedentary lifestyle and are often associated with testicular overheat, deserve special attention with respect to male fertility potential. Interestingly, the harmful effect of testicular heat stress on sperm characteristics including nuclear DNA integrity was well characterized; however, the influence of sedentary work on sperm chromatin has not yet been documented. Therefore, our research was designed to examine the potential effects of sedentary ...
(European Association of Urology) Scientists have found that sperm DNA from the testicles of many infertile men is as good as that of ejaculated sperm of fertile men. This may explain a major cause of male infertility and opens the possibility of using sperm taken directly from the testicles of these men; to overcome their infertility.
Condition: Infertility, Female Intervention: Diagnostic Test: Live birth rate Sponsor: Assisting Nature Recruiting
ConclusionThe prevalence of infertility in China is high, but the uptake of treatment is relatively low.
A study, published inHuman Reproduction, reports that women with fertility issues have a higher risk of developing cancer.Daily Mail