Airway Microbiota Is Associated with Up-Regulation of the PI3K Pathway in Lung Cancer.

CONCLUSIONS: The data presented here shows that several transcriptomic signatures previously identified as relevant to lung cancer pathogenesis are associated with enrichment of the lower airway microbiota with oral commensals.
PMID: 29864375 [PubMed - as supplied by publisher]

Source: American Journal of Respiratory and Critical Care Medicine - June 4, 2018 Category: Respiratory Medicine Authors: Tsay JJ, Wu BG, Badri MH, Clemente JC, Shen N, Meyn P, Li Y, Yie TA, Lhakhang T, Olsen E, Murthy V, Michaud G, Sulaiman I, Tsirigos A, Heguy A, Pass H, Weiden MD, Rom WN, Sterman DH, Bonneau R, Blaser MJ, Segal LN Tags: Am J Respir Crit Care Med Source Type: research