14-3-3 Proteins in Glutamatergic Synapses.

14-3-3 Proteins in Glutamatergic Synapses.
Neural Plast. 2018;2018:8407609
Authors: Zhang J, Zhou Y
Abstract
The 14-3-3 proteins are a family of proteins that are highly expressed in the brain and particularly enriched at synapses. Evidence accumulated in the last two decades has implicated 14-3-3 proteins as an important regulator of synaptic transmission and plasticity. Here, we will review previous and more recent research that has helped us understand the roles of 14-3-3 proteins at glutamatergic synapses. A key challenge for the future is to delineate the 14-3-3-dependent molecular pathways involved in regulating synaptic functions.
PMID: 29849571 [PubMed - in process]

Source: Neural Plasticity - June 6, 2018 Category: Neurology Authors: Zhang J, Zhou Y Tags: Neural Plast Source Type: research