Adenocarcinoma of the oesophagus: neoadjuvant chemoradiation and radical surgery

ConclusionNeoadjuvant CRT in patients with AC of the oesophagus followed by thoracoabdominal surgery is a  locally very effective concept. A significant tumour regression in almost 75% of the patients may stimulate prospective trials on the omission of radical surgery for some elderly patients. Due to a high rate of distant metastases further investigations in terms of effective systemic therapy may be warranted.
Source: Strahlentherapie und Onkologie - Category: Cancer & Oncology Source Type: research