Protein Kinase C- β Dictates B Cell Fate by Regulating Mitochondrial Remodeling, Metabolic Reprogramming, and Heme Biosynthesis

Lymphocyte activation is associated with major changes in metabolism. Tsui and colleagues demonstrate that PKC β promotes metabolic reprogramming to drive effector fate decision in B cells.

Source: Immunity - June 5, 2018 Category: Allergy & Immunology Authors: Carlson Tsui, Nuria Martinez-Martin, Mauro Gaya, Paula Maldonado, Miriam Llorian, Nathalie M. Legrave, Merja Rossi, James I. MacRae, Angus J. Cameron, Peter J. Parker, Michael Leitges, Andreas Bruckbauer, Facundo D. Batista Tags: Article Source Type: research