Time to deliver: report of the WHO Independent High-Level Commission on NCDs

This paper provides possible policy options and interventions on NCDs. Main NCDs include CVD, cancers, chronic respiratory diseases, and diabetes; these are largely preventable through public policies that tackle risk factors - tobacco, alcohol, unhealthy diet, and inactivity.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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(CNN) — The recommended amount of sleep for adults is six to eight hours a night. Sleeping more than those hours is associated with an increased risk of death and cardiovascular diseases, says a global study published Wednesday in the European Heart Journal. Looking at data from 21 countries, across seven regions, the research team found that people sleeping more than the recommended upper limit of eight hours increased their risk of major cardiovascular events, like stroke or heart failure, as well as death by up to 41%. But a possible reason for this could be that people have underlying conditions causing them to s...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Local TV Sleep Source Type: news
This report reviews the hepatoprotective effects of curcumin with a focus on its mechanistic insights in various hepatotoxic protocols. PMID: 30529260 [PubMed - as supplied by publisher]
Source: Food and Chemical Toxicology - Category: Food Science Authors: Tags: Food Chem Toxicol Source Type: research
AbstractBackground and AimsMost carcinoid tumors of the gastrointestinal tract are located in the small bowel (SB). Epidemiological studies of these tumors have been limited by small sample sizes. Our aim was to evaluate the epidemiology of SB carcinoids (SBCs) using a large database.MethodsWe queried a commercial database (Explorys), an aggregate of electronic health data from 26 US healthcare systems. We identified patients with SBCs between 2012 and 2017. We evaluated the epidemiology of SBC and identified possible risk factors.ResultsOf the 35,798,290 individuals in the database between 2012 and 2017, we identified 328...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
This report presents further evidence on the escalating alcohol consumption in the UK and the burden of liver disease associated with this major risk factor, as well as the effects on hospital and primary care. We reiterate the need for fiscal regulation by the UK Government if overall alcohol consumption is to be reduced sufficiently to improve health outcomes. We also draw attention to the effects of drastic cuts in public services for alcohol treatment, the repeated failures of voluntary agreements with the drinks industry, and the influence of the industry through its lobbying activities. We continue to press for reint...
Source: The Lancet - Category: General Medicine Source Type: research
BackgroundThe outcomes of older adults with acute lymphoblastic leukemia (ALL) remain poor when compared to younger ALL patients [PMID 19897583, 28419558, 22409379, 10653870]. Asparaginase (Asp) induces death of human lymphoblasts, and effective asparagine depletion is associated with improved outcomes in ALL. PEG-Asparaginase (PEG-Asp), which has a longer half-life than Asp, is a key component of the intensive chemotherapeutic regimens utilized for treatment of pediatric and younger adult ALL [PMID 29450465]. Frequently, older patients with Ph-negative ALL are not offered PEG-Asp containing pediatric chemotherapy regimen ...
Source: Blood - Category: Hematology Authors: Tags: 612. Acute Lymphoblastic Leukemia: Clinical Studies Source Type: research
Adult hemoglobin (HbA) is made up of two pairs of globin chains. Some rare mutations of the globin chains can result in high affinity towards hemoglobin molecule thus changing the equilibrium of normal oxygen loading in lungs and the delivery of same to the tissues. Because of change in the affinity to the oxygen these mutations can result in erythrocytosis (polycythemia). Here we discuss a case of Familial Polycythemia likely due to novel hemoglobin variant.42-year Caucasian male presents to the clinic with high hemoglobin for several years but otherwise denies any symptoms of headache, vision changes, chest pain. He had ...
Source: Blood - Category: Hematology Authors: Tags: 114. Hemoglobinopathies, Excluding Thalassemia-Clinical Source Type: research
Conclusion: Clinical features of TB in older patients may be atypical and confused with age-related diseases. Extensive pulmonary tuberculosis was often found in this group of patients.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
See something of interest? Please share our postings with colleagues in your institutions! Spotlight Deadline Extended! Apply by November 23 to participate in the 2019 Critical Appraisal Institute for Librarians! – Craving more confidence in leading EBM sessions for medical students? Puzzled on how to guide students about study design and in depth critical appraisal? Frustrated with statistics? This six week online program will develop librarian’s critical appraisal skills via enhanced understanding of research design, biomedical statistics, and clinical reasoning to apply knowledge in teaching target populatio...
Source: NN/LM Middle Atlantic Region Blog - Category: Databases & Libraries Authors: Tags: Weekly Postings Source Type: news
ConclusionsWe report the largest single ‐center study evaluating clinical, histopathological, and outcome measures of patients undergoing LT for steatohepatitis. Older patients, diabetics, and Hispanics may warrant more frequent cancer screening due to increased risk of HCC.This article is protected by copyright. All rights reserved.
Source: Liver International - Category: Gastroenterology Authors: Tags: Original Article Source Type: research
Conclusion Evidence of clinical benefit of most available apps is very limited. Design features that enhance usability and maximise efficacy were identified. A provisional 'first-pass' evaluation framework is proposed that can help decide which apps should be endorsed by government agencies following more detailed technical assessments and which could then be recommended with confidence by clinicians to their patients.What is known about the topic? Smartphone health apps have attracted considerable interest from patients and health managers as a means of promoting more effective self-management of chronic diseases, which l...
Source: Australian Health Review - Category: Hospital Management Authors: Tags: Aust Health Rev Source Type: research
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