Relationships between sunitinib plasma concentration and clinical outcomes in Japanese patients with metastatic renal cell carcinoma
ConclusionsThe present study demonstrated that the effective range of total sunitinib concentration in Japanese patients with mRCC was lower than 50 –100 ng/mL which was previously reported. These results indicate that therapeutic drug monitoring could maintain the therapeutic effect of sunitinib while minimizing adverse events by personalizing sunitinib dosages for Japanese patients with mRCC.
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
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