An RI angiographic approach to estimate cardiac blood pool contribution to heart ROI radioactivity of planar 123I-MIBG myocardial scintigraphy

Conclusion: The additional RI angiography study of MIBG can readily be part of routine planar imaging practice for investigation of myocardial catecholamine innervation. In this small cohort study, BMIs was not a good predictor of blood pool radioactivity fractions to correct contaminated heart ROI count rates. Although breast attenuation is individually variable, we conclude that the heart ROI radioactivity of the female group might be underestimated compared with that of the male group. Based on the RAUC results, subtracting mediastinum ROI radioactivity multiplied by unity seems to be reasonably valid. However, it might be another source of underestimation of specific myocardial MIBG accumulation for the patients with low RAUC.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Cardiovascular Clinical Science Poster Session Source Type: research