Assessment of bone turnover in multiple myeloma patients before and after treatment.

Conclusion: The significant decrease in GSUVmean and GSUVmax of the MM patients in the HDT group seems to indicate that the aggressive treatment in these patients was successful in decreasing the number of myeloma lesions and possibly decreasing the incidence of insufficiency fractures, which can augment the uptake of NaF. Furthermore, chemotherapy can decrease the uptake of NaF, and as a result, high dose chemotherapy could have directly caused lower uptake of NaF. Further studies involving larger samples are needed to confirm our findings.

Source: Journal of Nuclear Medicine - May 23, 2018 Category: Nuclear Medicine Authors: Zirakchian Zadeh, M., Raynor, W., Oestergaard, B., Taghvaei, R., Acosta-Montenegro, O., Mehdizadeh Seraj, S., Saboury, B., Al-zaghal, A., Yellanki, D., Ayubcha, C., Werner, T., Abildgaard, N., Zhuang, H., Hoilund-Carlsen, P. F., Alavi, A. Tags: Leukemia/Lymphoma/Myeloma Poster Session Source Type: research