Evaluation of L-1-[18F]Fluoroethyl-Tryptophan for PET Imaging of Cancer

Conclusions: L-1-[18F]FETrp highly accumulates in a wide range of malignancies including lung cancer, prostate cancer, and brain tumor. These PET imaging results suggested that L-1-[18F]FETrp is a promising radiotracer for cancer imaging. Research Support:This work was supported by the Simmons Cancer Center Grant (NIH 5P30 CA 142543), and American Cancer Society and the Simmons Cancer Center (ACS-IRG-02-196).Reference: Xin, Y. & Cai, H. Improved Radiosynthesis and Biological Evaluations of L- and D-1-[18F]Fluoroethyl-Tryptophan for PET Imaging of IDO-Mediated Kynurenine Pathway of Tryptophan Metabolism. Mol. Imaging Biol.19, 589-598 (2017).

Source: Journal of Nuclear Medicine - May 23, 2018 Category: Nuclear Medicine Authors: Xin, Y., Gao, X., Liu, L., Ge, W.-P., Cai, H. Tags: Basic Science Posters (Oncology) Source Type: research