Identify sarcoid-like reaction in cancer patients receiving chemotherapy and immunotherapy: dont get into the weeds of SUVmax

Conclusions: To avoid pitfall in PET/CT interpretation, it is important to recognize the sarcoid-like pattern of FDG uptake, which regardless of SUV value is favored to represent a benign rather than a malignant process.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Educational Exhibits Source Type: research

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ConclusionAbdominal irAEs were detected on CT in 13% of NSCLC patients treated with nivolumab, and colitis, in the pancolitis form, was the most common irAE. Given the expanding role of immunotherapy, radiologists should be aware of the frequency and imaging manifestations of abdominal irAEs and the impact on patient management.
Source: Abdominal Imaging - Category: Radiology Source Type: research
How could a country keep around 1.4 billion people healthy when the system struggles with corruption, lack of resources and an aging population? China, the emerging giant with a strong central leadership fostering technology and innovation, places its bets on artificial intelligence, telemedicine, cloud-based hospitals, and WeChat. While that could sound like an ultimate technological paradise, the question is, what are they going to do with the vast amount of data or to what interests are they going to leverage their state of the art A.I. systems? Generally, how will we speak about digital health in China: a healthcare dy...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence in Medicine Bioethics Future of Medicine Medical Professionals Patients Policy Makers AI chatbot china digital digital health Healthcare Innovation smartphone technology telehealth telemedicine Source Type: blogs
Conditions:   Sarcoidosis;   Cancer Intervention:   Sponsor:   University of Miami Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Vergnon JM, Tissot CL PMID: 30745234 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
Much has been researched and written about the promise of PET/MRI. While the...Read more on AuntMinnie.comRelated Reading: Ga-68 PSMA-11 PET/MRI benefits prostate cancer patients TOF PET/MRI makes dose reduction viable for breast cancer How effective is PET/MRI for rectal cancer? PET/MRI with ferumoxytol MR contrast performs well for pediatric patients Cardiac FDG-PET/MRI's role in Anderson-Fabry disease
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
We describe a 16-year-old high school student referred for management of achalasia who turned out to have pseudoachalasia due to adenocarcinoma of the cardia. He was cured with preoperative chemotherapy followed by radical surgery. Therapy of pseudoachalasia secondary to neoplasia is directed against the tumor or may be palliative to keep the lumen open. Other causes of pseudoachalasia include esophageal motility disturbances as a paraneoplastic phenomenon (e.g., with small cell lung cancer), post fundoplication or post bariatric surgery, in association with a thoracic aortic aneurysm, or with sarcoidosis or amyloidosis. T...
Source: Digestive Diseases - Category: Gastroenterology Source Type: research
ConclusionBased on our findings, 10% patients in the interim or late PET/CT showed ‘sarcoid-like lymphadenopathy’ as response to treatment. All these patients showed disease control, implying a relation between the appearance of sarcoid-like lymphadenopathy and the clinical benefit of anti-CTLA-4 therapy. On the other hand, quantitative18F-FDG PET analysis of the spleen showed a poor performance in predicting clinical benefit to ipilimumab.
Source: Cancer Immunology, Immunotherapy - Category: Cancer & Oncology Source Type: research
Abstract A 69-year-old woman was diagnosed with sarcoidosis, which was not treated with corticosteroid therapy. Her levels of angiotensin converting enzyme decreased significantly over 4 years and a mass lesion was detected near the lower part of her left main bronchus, and diagnosed as small cell lung cancer (SCLC). Treatment of the SCLC with a series of chemotherapeutic agents produced excellent results. The pulmonary sarcoidosis did not show any deterioration despite the frequent use of amrubicin, which is known to be a cause of interstitial pneumonia. This is a case report of SCLC complicated with sarcoidosis ...
Source: Journal of Nippon Medical School - Category: Universities & Medical Training Authors: Tags: J Nippon Med Sch Source Type: research
In conclusion, using newer sensitive imaging tool we detected 36 (9.2%) patients with serious pathologies before the first symptoms. Therefore we believe, that ¹F-FDG PET/CT imaging can be recommended to be done not only in all MGUS patients with suspected SMM or active MM, but also for early identification of other serious pathologies.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - Category: Hematology Authors: Tags: 651. Myeloma: Biology and Pathophysiology, excluding Therapy: Poster I Source Type: research
Conclusion: The pillars of radiological diagnosis of destructive pulmonary TB are less thickness of the cavity wall, even interior contouring, rounded polygonal form. Non-tuberculous and cancer cavities are characterized by thicker walls, uneven interior contouring, polygonal fissured form.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
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