Fluciclovine PET Imaging of Intracranial Metastases

Conclusions: PET imaging with radiolabeled amino acids has been shown be effective for brain tumor imaging, providing high contrast between tumor and normal brain parenchyma. The synthetic leucine amino acid analogue, fluciclovine has been recently FDA approved for evaluation of biochemical recurrent prostate cancer. Recent studies have been published demonstrating the utility of fluciclovine for glioma evaluation. Our findings suggest that fluciclovine can similarly be used for evaluation of new or recurrent brain metastasis in patients who previously have undergone brain radiotherapy where MRI is often limited due to background post-treatment changes.

Source: Journal of Nuclear Medicine - May 23, 2018 Category: Nuclear Medicine Authors: Patel, D., Nye, J., Schuster, D., Olson, J., Goodman, M., Parent, E. Tags: Preclinical Probes for Oncology Posters Source Type: research