Dual Gastrin-Releasing Peptide Receptor and Integrin {alpha}v{beta}3 targeting PET/CT using 68Ga-BBN-RGD in Patients with Breast Cancer

Conclusion: This study demonstrated significant uptake of a new type of dual integrin αvβ3 and GRPR targeting radiotracer in both the primary lesion and the metastases of breast cancer. 68Ga-BBN-RGD PET/CT may be of great value in discerning both primary breast cancers, axillary lymph nodes metastasis and distant metastases, which indicates the efficacy of 68Ga-BBN-RGD PET/CT in breast cancer diagnosis, staging and therapy planning for the patients.

Source: Journal of Nuclear Medicine - May 23, 2018 Category: Nuclear Medicine Authors: Zhang, J., Mao, F., Niu, G., Peng, L., Lang, L., Li, F., Ying, H., Wu, H., Zhu, Z., Chen, X. Tags: First-in-Human & amp; New Human Applications Source Type: research