The Effect of Total Tumor Volume on the Biologically Effective Dose to Tumor and Kidneys for 177Lu-Labeled PSMA Peptides

Conclusion: This simulation study suggests that in patients with large PSMA-positive tumor volumes, higher activities and peptide amounts can be safely administered to maximize tumor BEDs without exceeding the tolerable BED to the organs at risk.

Source: Journal of Nuclear Medicine - June 1, 2018 Category: Nuclear Medicine Authors: Begum, N. J., Thieme, A., Eberhardt, N., Tauber, R., DAlessandria, C., Beer, A. J., Glatting, G., Eiber, M., Kletting, P. Tags: Clinical Source Type: research