Surveillance of influenza and other respiratory viruses in the UK: Winter 2017-18

This report describes influenza activity experienced in UK from week 40, 2017 to week 15, 2018 and includes observations and commentary from the childhood vaccination programme and activity of other seasonal and novel respiratory viruses.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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Abstract Influenza viruses A and B are important human respiratory pathogens causing seasonal, endemic and pandemic infections in several parts of the globe with high morbidity and considerable mortality. The current inactivated and live attenuated vaccines are not effective. Therefore, it is of interest to design universal influenza virus vaccines with high efficacy. The peptide GQSVVSVKLAGNSSL of pandemic influenza, the peptide DKTSVTLAGNSSLCS of seasonal influenza and the peptide DILLKFSPTEITAPT of influenza B were identified as potential linear cell mediated epitopes. The epitopes predicted by BepiPred (B-cell...
Source: Bioinformation - Category: Bioinformatics Authors: Tags: Bioinformation Source Type: research
Abstract Once neglected in research and underappreciated in practice, there is renewed interest in bronchiectasis unrelated to cystic fibrosis. Bronchiectasis is a chronic lung disease characterised by chronic cough, sputum production and recurrent pulmonary exacerbations. It is diagnosed radiologically on high resolution computed tomography chest scan by bronchial dilatation (wider than the accompanying artery). The causes of bronchiectasis are diverse and include previous respiratory tract infections, chronic obstructive pulmonary disease, asthma, immunodeficiency and connective tissue diseases. A large proporti...
Source: Med J Aust - Category: General Medicine Authors: Tags: Med J Aust Source Type: research
Pfizer has agreed to pay German biotech firm BioNTech up to $425 million in an alliance to develop more effective influenza jabs, the latest among several major pharma companies to bank on a promising new genetic approach.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Authors: Seale H PMID: 30106607 [PubMed - as supplied by publisher]
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
Pulmonary immunization with a recombinant influenza A virus vaccine induces lung-resident CD4+ memory T cells that are associated with protection against tuberculosis, Published online: 16 August 2018; doi:10.1038/s41385-018-0065-9Pulmonary immunization with a recombinant influenza A virus vaccine induces lung-resident CD4+ memory T cells that are associated with protection against tuberculosis
Source: Mucosal Immunology - Category: Allergy & Immunology Authors: Source Type: research
Condition:   Healthy Volunteers (Meningococcal Infection) Interventions:   Biological: Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine MenACYW conjugate vaccine;   Biological: Meningococcal (Groups A, C, Y and W 135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine;   Biological: Measles, Mumps, and Rubella Virus Vaccine L ive;   Biological: Varicella Virus Vaccine;   Biological: Pneumococcal 13-valent Conjugate Vaccine;   Biological: Diphtheria, tetanus, pertussis (acellular component), hepatitis B, poliomyelitis ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions: ACs readily accepted influenza vaccination at their child’s pediatric primary care office. Increased vaccination acceptance occurred when ACs were female, had private insurance, if their child had a chronic illness and if the vaccination was offered the same day as their child’s appointment. Likely reason for low acceptance in ACs with Medicaid insurance is high cost; thus, staff, well-aware of Medicaid’s nonreimbursement, likely offered the vaccine less to these parents.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Vaccine Reports Source Type: research
Every Vaccine You Need After Age 50 ... There are three vaccines every adult needs — Influenza, Tdap, and Shingles. Two others, Hepatitis A and Hepatitis B — are needed for certain risk factors. .....
Source: AARP.org News - Category: American Health Source Type: news
Prenatal infection is a substantial risk factor for neurodevelopmental disorders such as autism in offspring. We have previously reported that influenza vaccination (VAC) during early pregnancy contributes to ...
Source: Journal of Neuroinflammation - Category: Neurology Authors: Tags: Research Source Type: research
Publication date: Available online 11 August 2018Source: Veterinary MicrobiologyAuthor(s): Mohamed Dilai, Mohammed Piro, Stéphanie Fougerolle, Mehdi El Harrak, Wissal Mahir, Rachida El Mourid, Loïc Legrand, Romain Paillot, Ouafaa Fassi FihriAbstractIn order to evaluate the vaccination status against equine influenza (EI) in Moroccan racehorses, a serological investigation was carried out on 509 racehorses using three serological tests: an Enzyme-Linked Immunosorbent Assay (ELISA), the Hemagglutination Inhibition (HI) test and the Single Radial Haemolysis (SRH) assay. The serological analysis showed 56% of serop...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
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